What is the scientific name of mouse?
Mus musculus
House mouse/Scientific names
What is an ICR mouse?
The ICR mouse is a strain of albino mice originating in SWISS and selected by Dr. Hauschka to create a fertile mouse line. Because mice of this strain have been sent to various places from the Institute of Cancer Research in the USA, the strain was named ICR after the initial letters of the institute.
What are Swiss mice?
Also Known As:SW, Swiss Inbred Aging mice exhibit a high incidence of lung and mammary gland tumors. They also develop extreme polydipsia and polyuria (nephrogenic diabetes insipidus) with increasing age. SWR/J mice are highly susceptible to experimental allergic encephalomyelitis.
Why do we use Swiss albino mice in laboratory?
Swiss Albino is usually used in toxicology studies. Swiss being an outbred animal, is suitable for toxicology as it has variability between animals. However, if you take other inbred animals such as BALB/c, C57BL/6, etc, they are very similar and you would not have so much variations between animals.
What is another name for a mouse?
In this page you can discover 39 synonyms, antonyms, idiomatic expressions, and related words for mouse, like: rat, rodent, pussyfoot, animal, slip, shiner, murine, prowl, gumshoe, skulk and slide.
Is a mouse a marsupial?
They are sometimes also called broad-footed marsupial mice, pouched mice, route rat or Antechinus shrews. However, these common names are considered either regional or archaic and the modern common name for the animals is antechinus….
| Antechinus | |
|---|---|
| Kingdom: | Animalia |
| Phylum: | Chordata |
| Class: | Mammalia |
| Infraclass: | Marsupialia |
Why are BALB mice immunodeficient?
This mouse is inbred, and genetic monitoring results confirm it to be a BALB/c nude. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.
Are BALB c mice inbred?
BALB/c Mouse BALB/c mice are inbred strain and now over 230 generations from their origin in New York in 1920. BALB/c mice are distributed globally and among the five most widely used inbred strains in biomedical research, particularly in immunology and infectious disease research.
What are outbred mice?
Outbred mice are called stocks, which are defined as a closed population (for at least four generations) of genetically variable mice that are bred to maintain maximal heterozygosity. From: Laboratory Animal Medicine (Third Edition), 2015.
Are ICR mice outbred?
ICR mice are one the most commonly available outbred population because they have good reproductive performance, are inexpensive, robust, and grow rapidly [5,6].
Where did the Swiss albino mouse come from?
The widely distributed Swiss albino mice, largely noninbred, are mainly derived from two males and seven females which Clara J. Lynch of the Rockefeller Institute obtained from A. de Coulon of Lausanne in 1926 (Lynch, 1961, personal communication). The original stock probably came from Paris.
Why are the majority of laboratory mice albino?
Albinism of laboratory rodents: The majority of laboratory rodents are albinos, due to a common mutation in tyrosinase gene in all albino laboratory rat strains [16] and in at least some of the albino mouse strains [17]. Tyrosinase is the rate-limiting enzyme in the production of melanin pigment.
Where did the Swiss mouse strain come from?
The strain was created from 2 outbred albino males and 7 outbred albino females originating from the “Centre Anticancéreux de Romand” (Lausanne, Switzerland) and imported to the Rockfeller Institute by Lynch (1926). The offspring are scattered around the world.
Why are SOPF Swiss mice used in research?
The offspring are scattered around the world. Carworth Farm selected one line of mice for its vigour and productivity (1935). Versatile outbred mouse, used in all areas of biomedical research (general studies), it is used as donor and/or recipient of embryos. SOPF SWISS mice are ideal sentinels because they will readily seroconvert.