What does rhabdoid features mean?
Rhabdoid morphology is classically defined as “sheets and clusters of variably cohesive, large epithelioid cells with vesicular nuclei, prominent nucleoli and large paranuclear intracytoplasmic inclusions” (Am J Surg Pathol 2000;24:1329)
What does sarcomatoid mean?
Almost any type of renal cell cancer can become sarcomatoid. This means that the cells of the cancer look like the cells of a sarcoma (cancer of the connective tissues, such as muscles, nerves, fat, blood vessels and fibrous tissue).
What does rhabdoid mean?
: a rod-shaped protoplasmic body in the sensitive cells of leaves of various plants of the family Droseraceae.
What is sarcomatoid morphology?
Sarcomatoid morphology by definition is WHO / ISUP grade 4. Wavy or rhabdoid regions that maintain epithelial features should not be considered sarcomatoid (Am J Surg Pathol 2004;28:435)
What are sarcomatoid features?
Renal cell carcinoma (RCC) with sarcomatoid differentiation (sRCC) is a highly aggressive form of RCC. Histologically, sRCC shows loss of characteristic epithelial components and contains features such as spindle cells, high cellularity, and cellular atypia.
Is a rhabdoid tumor a sarcoma?
Rhabdoid tumor (RT) is an aggressive pediatric soft tissue sarcoma that arises in the kidney, the liver, the peripheral nerves and all miscellaneous soft-parts throughout the body. RT involving the central nervous system (CNS) is called atypical teratoid rhabdoid tumor. RT usually occurs in infancy or childhood.
What is sarcomatoid neoplasm?
Sarcomatoid carcinoma is a rare form of cancer in which the cells exhibit properties characteristic of both epithelial and mesenchymal tumors; it can occur in multiple organs, including skin, bone, thyroid, breast, liver, pancreas, urinary tract, and lung [1].
Is Sarcomatoid the same as sarcoma?
Sarcomatoid carcinoma, sometimes referred to as pleomorphic carcinoma, is a relatively uncommon form of cancer whose malignant cells have histological, cytological, or molecular properties of both epithelial tumors (“carcinoma”) and mesenchymal tumors (“sarcoma”)….
| Sarcomatoid carcinoma | |
|---|---|
| Specialty | Oncology |