Who manufactures sofosbuvir?
Sofosbuvir is manufactured as Sovaldi (soh-VAHL-dee) by Gilead Sciences (Figure 1) and (Figure 2). The drug sofosbuvir was previously known as GS-7977 and was originally developed by Pharmasset as compound PSI-7977.
How much does sofosbuvir cost?
Sofosbuvir (Sovaldi): This medication costs $1,000 per 400 mg pill. The total cost for a 12-week course is around $84,000, and doctors will typically prescribe it with other medicines, such as simeprevir.
What type of inhibitor is sofosbuvir?
Key findings: Sofosbuvir is a novel nucleotide analogue inhibitor of hepatitis C virus (HCV) NS5B polymerase that has recently been approved by the Federal Drug Administration for the treatment of HCV genotypes 1, 2, 3 or 4 in a variety of patients.
What is the brand name for sofosbuvir?
Sofosbuvir, sold under the brand name Sovaldi among others, is a medication used to treat hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir, daclatasvir, or velpatasvir.
How much is Sovaldi in India?
Gilead Sciences makes the hepatitis C drugs – Sovaldi and Harvoni – but $85,000 is an only in America price. Sovaldi sells for about $1,000 a pill in the U.S., while a generic version costs only $4 a pill in India.
Is sofosbuvir generic?
Harvoni’s new generic is ledipasvir/sofosbuvir and Epclusa’s new generic is velpatasvir/sofosbuvir. Both of these new generics are exact replicas of their brand-name counterparts, with the same forms and strengths.
What class drug is sofosbuvir?
Sofosbuvir is a nucleotide analogue inhibitor and ledipasvir is an HCV inhibitor; they reduce viral load by inhibiting hepatitis C virus RNA replication.
Is sofosbuvir a biologic?
In December of 2013, Sovaldi (sofosbuvir) and Olysio (simeprevir) were approved by the United States Food and Drug Administration. The chemical composition of both Sovaldi and Olysio are different than traditional medications in that they are biologics.
How much does Mavyret cost in India?
Mavyret Glecaprevir Pibrentasvir 100 mg/40 mg at Rs 13055/strip | Nagpur| ID: 21558190862.