When is Isuprel used?
Isuprel is a prescription medicine used to treat the symptoms of Adams-Stokes Attacks, Cardiac Arrest, or Heart Block, Shock, and Bronchospasm during Anesthesia. Isuprel may be used alone or with other medications.
What is Isuprel used for?
Isuprel (isoproterenol hydrochloride) is a bronchodilator used as an inhaler to treat conditions such as asthma, bronchitis, and emphysema. In rare cases, Isuprel is given as an injection as a treatment for electrical heart block.
How do you mix Isuprel?
dilute 1 mL of 1:5000 (0.2 mg/mL) to a volume of 10 mL with dextrose 5% or sodium chloride 0.9% ((final concentration of 20 mcg/mL)…Monitoring Therapy:
- IV site.
- continuous heart rate and ECG rhythm.
- blood pressure.
- urine output.
- central or mixed venous oxygen saturation.
- lactate.
- blood gases.
- cardiac output if monitored.
What is the action of isoproterenol?
Isoproterenol is a beta-1 and beta-2 adrenergic receptor agonist resulting in the following: Increased heart rate. Increased heart contractility. Relaxation of bronchial, gastrointestinal, and uterine smooth muscle.
Why is Isuprel so expensive?
It is very expensive. According to a statement posted in April 2015 by the Heart Rhythm Society,1 the increased costs are not due to a shortage of supply. “Several years ago, Marathon Pharmaceuticals bought isoproterenol from Hospira. The cost of Isuprel continues to escalate, with its price now at $1,356 per vial.
Is Isuprel an Inotrope?
Isoprenaline has positive inotropic and chronotropic effects on the heart. β2 adrenoceptor stimulation in arteriolar smooth muscle induces vasodilation. Its inotropic and chronotropic effects elevate systolic blood pressure, while its vasodilatory effects tend to lower diastolic blood pressure.
Is isuprel an Inotrope?
What is the generic of isuprel?
Nexus Pharmaceuticals’ version of isoproterenol hydrochloride is available as a single-dose vial containing 0.2 mg per 1 mL or 1 mg per 5 mL and is an AP-rated (therapeutically equivalent) generic equivalent of Isuprel, the company said in a news release.
Does dobutamine increase blood pressure?
Dobutamine may cause a marked increase in heart rate or blood pressure, especially systolic pressure. Approximately 10% of patients in clinical studies have had rate increases of 30 beats/minute or more, and about 7.5% have had a 50 mm Hg or greater increase in systolic pressure.
How much does isuprel cost?
The cost for Isuprel injectable solution (0.2 mg/mL) is around $18,698 for a supply of 50 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Isuprel is available, see isoproterenol prices.