What is struma ovarii?
INTRODUCTION. Struma ovarii is a specialized or monodermal teratoma predominantly composed of mature thyroid tissue [1]. Thyroid tissue must comprise more than 50 percent of the overall tissue to be classified as a struma ovarii. Struma ovarii accounts for approximately 5 percent of all ovarian teratomas [2-4].
Is struma ovarii benign?
The vast majority of strumae ovarii are benign, but malignant disease is found in a small percentage of cases, the most common being papillary thyroid carcinoma. The symptoms of struma ovarii are similar to those of other ovarian tumors and are nonspecific in nature.
Is struma ovarii a dermoid cyst?
Struma ovarii is a rare histological diagnosis, a variant of dermoid in which thyroid tissue constitute >50% of the component,[1] also called as monodermal ovarian teratoma where thyroid tissue predominates.
Is Struma Ovarii malignant?
Background: Struma ovarii is a rare monodermal ovarian teratoma composed predominantly of mature thyroid tissue. Of these cases, 5-8% are clinically hyperthyroid and 5-10% of these tumors are malignant.
How is a Struma Ovarii diagnosed?
The diagnostic criterion of malignant struma ovarii is based on histological features of the resected ovary. Although not yet uniformly standardized, these criteria include cellular atypia and increased hyperplasia, nuclear pleomorphism, mitotic activity, and vascular and/or capsular invasion.
Is struma ovarii malignant?
How is struma ovarii treated?
Simple surgery is recommended for patients with struma ovarii, especially if they have fertility potential. Laparoscopic surgery is the recommended approach due to its shorter recovery time and lower morbidity. Most patients do not require extended periods of follow-up or postoperative investigations.
How is Struma Ovarii treated?
How do you get hyperthyroidism?
Normally, your thyroid releases the right amount of hormones, but sometimes it produces too much T4. This may occur for a number of reasons, including: Graves’ disease. Graves’ disease is an autoimmune disorder in which antibodies produced by your immune system stimulate your thyroid to produce too much T4.
How do you know if a teratoma is cancerous?
Your doctor may also request tests such as: X-ray, ultrasound, bone scans, MRI, and CT to see where the tumor is and contain its spread. Blood tests to check hormone levels that may indicate the presence of a tumor. Biopsy to see if the teratoma is cancerous.
What kind of tissue is in A struma ovarii?
Struma ovarii is a specialized or monodermal teratoma predominantly composed of mature thyroid tissue [ 1 ]. Thyroid tissue must comprise more than 50 percent of the overall tissue to be classified as a struma ovarii.
Where does radioiodine uptake occur in struma ovarii?
Radioiodine uptake is low or absent in the thyroid gland but present in the pelvis. Rarely, women with struma ovarii and hyperthyroidism also have a goiter [ 7 ]. There are at least two possible explanations for this association:
How old do you have to be to have struma ovarii?
The clinical manifestations of struma ovarii are based upon single case reports and small case series [ 2-5,9,10 ]. General findings — Struma ovarii is most common between the ages of 40 and 60 years, but has been reported in patients as young as 10 years old [ 11 ].
Can a woman with struma ovarii have ascites?
Ovarian teratomas are reviewed in detail elsewhere. (See “Ovarian germ cell tumors: Pathology, epidemiology, clinical manifestations, and diagnosis”, section on ‘Teratomas’ .) Women with struma ovarii usually present with pain and/or a pelvic mass and less frequently with ascites.