What is the etiologic agent of smallpox?
INFECTIOUS AGENT Smallpox is caused by variola virus, genus Orthopoxvirus. Other members of this genus that can infect humans are vaccinia virus, monkeypox virus, and cowpox virus.
What is the smallpox vaccine made from?
The vaccine is made from a virus called vaccinia, which is a poxvirus similar to smallpox, but less harmful. The smallpox vaccine contains live vaccinia virus, not a killed or weakened virus like many other vaccines.
What is responsible for smallpox vaccination?
The smallpox vaccine, introduced by Edward Jenner in 1796, was the first successful vaccine to be developed. He observed that milkmaids who previously had caught cowpox did not catch smallpox and showed that inoculated vaccinia protected against inoculated variola virus.
What kind of virus is used to make a smallpox vaccine?
The smallpox vaccine helps the body develop immunity to smallpox. The vaccine is made from a virus called vaccinia which is a “pox”-type virus related to smallpox.
What is the causative agent of chickenpox?
Chickenpox is a highly contagious disease caused by the varicella-zoster virus (VZV).
Why was the smallpox vaccine invented?
The smallpox vaccine was the first vaccine to be developed against a contagious disease. In 1796, the British doctor Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus….MVA-BN.
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ChemSpider | none |
When was ACAM2000 made?
The U.S. Food and Drug Administration (FDA) approved ACAM2000 in August 2007. By February 2008, it replaced Dryvax for all smallpox vaccinations. As of 2010, there were over 200 million doses manufactured for the U.S. Strategic National Stockpile.
Who invented the vaccinations?
Edward Jenner is considered the founder of vaccinology in the West in 1796, after he inoculated a 13 year-old-boy with vaccinia virus (cowpox), and demonstrated immunity to smallpox. In 1798, the first smallpox vaccine was developed.