What does reactive mesothelial cells present mean?
Reactive Mesothelial Cells. Reactive mesothelial cells can be found when there is an infection or an inflammatory response present in a body cavity. This condition can be due to the presence of a bacterial, viral, or fungal infection. It can also be the result of trauma or the presence of metastatic tumor.
What causes reactive mesothelial cells?
There are many causes of reactive mesothelial cells including: infection, inflammation, infarction, liver disease, radiation, chemotherapy, systemic disease, trauma, foreign materials, and neoplasia (DeMay 2012).
What is mesothelial cells in ascitic fluid?
Human peritoneal mesothelial cells (HPMCs) form the peritoneal lining and serve as a protective anatomical barrier. They are among the most abundant cell type in ascites from patients with OC [13].
Is malignant ascites curable?
For most patients, development of malignant ascites signals advanced, incurable cancer. Often, there may be no suitable cure for the underlying cancer. However, for some cancers (eg, ovarian cancer, lymphoma), treating the underlying cancer with chemotherapy and/or surgery may control ascites as well.
Is malignant ascites bad?
The development of malignant ascites carries a poor prognosis, with the median survival reported anywhere between 1 and 4 months. Patients with malignant ascites clinically present similarly to those with ascites secondary to cirrhosis.
Are there reactive mesothelial cells in pleural fluid?
Numerous reactive mesothelial cells were present in only 1,2% of specimens examined. In contrast, 65,3% of pleural fluid aspirates obtained from a control group of patients in congestive cardiac failure contained marked mesothelial exfoliation.
What is the definition of peritoneal fluid in horses?
Peritoneal Fluid. Peritoneal fluid is an ultrafiltrate of plasma, which serves as a lubricant around abdominal organs and allows the diffusion of electrolytes and other substances to and from the serosal surfaces of the abdominal cavity. From: Clinical Veterinary Advisor: The Horse, 2012.
How are mesothelial cells used in medical research?
Mesothelial cells The ability to propagate mesothelial cells in culture has resulted, over the past two decades, in an explosion of mesothelial cell research pertaining to PD and peritoneal disorders. Independent researchers have highlighted the potential use of mesothelial cells as targets for gene therapy or transp …
Why is the mesothelium important to the peritoneal cavity?
Results: The mesothelium is now considered to be a dynamic membrane that plays a pivotal role in the homeostasis of the peritoneal cavity, contributing to the control of fluid and solute transport, inflammation, and wound healing. These functional properties of the mesothelium are compromised in the setting of PD.