What is proflavine used for?
Topical antiseptic used mainly in wound dressings. Proflavine is an acriflavine derivative which is a disinfectant bacteriostatic against many gram-positive bacteria. Proflavine is toxic and carcinogenic in mammals and so it is used only as a surface disinfectant or for treating superficial wounds.
Which chemical nucleus is present in proflavine?
It has been used in the form of the dihydrochloride and hemisulfate salts as a topical antiseptic, and was formerly used as a urinary antiseptic. Proflavine is also known to have a mutagenic effect on DNA by intercalating between nucleic acid base pairs….Proflavine.
| Names | |
|---|---|
| Chemical formula | C13H11N3 |
| Molar mass | 209.252 g·mol−1 |
What is the solubility of proflavine in water?
Structure for Proflavine hemisulfate (DBSALT001573)
| Property | Value | Source |
|---|---|---|
| Water Solubility | 0.104 mg/mL | ALOGPS |
| logP | 2.1 | ALOGPS |
| logP | 1.85 | ChemAxon |
| logS | -3.3 | ALOGPS |
What is mechanism of action proflavine?
The key mechanism of action of proflavine is by generating reactive oxygen species (ROS). Generation of ROS leading to release of free radicals is further induced by photo illumination/sunlight.
What is brand name of Proflavine?
Proflavine Hemisulphate and Cetrimide Cream, Packing Size: 15 g
| Brand | Centurion |
|---|---|
| Dosage Form | Ointment |
| Usage/Application | Personal |
| Categories | Allopathic |
| Type Of Packing | collapsible tube |
Which is Colour of Proflavine?
A synthetic acridine dye, deep orange in colour, formerly used as an antiseptic wound dressing. Proflavine intercalates into DNA and is a mutagen.
What is the chemical name of Proflavine?
Proflavine
| PubChem CID | 7099 |
|---|---|
| Molecular Formula | C13H11N3 |
| Synonyms | Proflavine acridine-3,6-diamine Proflavin 3,6-Diaminoacridine 92-62-6 More… |
| Molecular Weight | 209.25 |
| Dates | Modify 2021-11-20 Create 2005-03-26 |
What is the stability and storage of Proflavine?
Solutions stored at room temperature were chemically stable up to six months (94-105%). Conclusion: Proflavine solutions at concentration of 0.01% were chemically and physically stable for at least 12 months under refrigeration. The solution was chemically stable for six months when stored at room temperature.
What is the structure of Proflavine?
C13H11N3
Proflavine/Formula