What are the secretions of the chief cells?
The chief cells secrete pepsinogen, a moderately sized zymogen protein with a molecular weight of 40,400. Pepsin, an enzyme with a molecular weight of 32,700, is formed in the acidic environment of the stomach when pepsinogen loses its activation peptides.
What is the secretion of parietal cells?
The parietal cells are located in the middle part of the glands of the fundus-body region of the stomach. They secrete gastric acid, i.e. hydrochloric acid (approximately 0.16 M, pH ≥ 0.8) and secrete the intrinsic factor, which is a vitamin B12-binding protein.
What do parietal cells secrete and what is the function?
Parietal cells (also known as oxyntic cells) are epithelial cells in the stomach that secrete hydrochloric acid (HCl) and intrinsic factor. They contain an extensive secretory network of canaliculi from which the HCl is secreted by active transport into the stomach.
What do chief cells secrete and what is the function?
What is a Chief Cell? A gastric chief cell (AKA a zymogenic cell) is a type of epithelial cell located in the stomach lining. Its primary function is to synthesize and secrete pepsinogen; the inactive precursor to the enzyme pepsin, which is activated upon contact with hydrochloric acid.
What are the secretions of the chief cells and parietal cells and list the functions of each secretion?
The two main types of exocrine secretory cells of the stomach are parietal cells and chief cells. Parietal cells secrete hydrochloric acid and chief cells secrete digestive enzymes such as pepsin. These cells secrete their products when activated by signals from the body such as hormones and neurotransmitters.
What do chief cells secrete quizlet?
Chief cells secrete Gastric Lipase which functions to break down fats into smaller fatty acids that can be further digested in the intestine.
What is the function of the parietal cells?
Parietal cells are responsible for gastric acid secretion, which aids in the digestion of food, absorption of minerals, and control of harmful bacteria.
What do parietal cells produce?
The best-known component of gastric juice is hydrochloric acid, the secretory product of the parietal, or oxyntic cell. It is known that the capacity of the stomach to secrete HCl is almost linearly related to parietal cell numbers.
Do parietal cells secrete mucus?
These cells secrete a bicarbonate-rich mucus that coats and lubricates the gastric surface, and serves an important role in protecting the epithelium from acid and other chemical insults. Acid: Hydrochloric acid is secreted from parietal cells into the lumen where it establishes an extremely acidic environment.