What are cleaved lymphocytes?
Small cleaved cells are a distinctive type of cell that appears in certain types of lymphoma. When used to uniquely identify a type of lymphoma, they are usually categorized as follicular (C82.
What is a cleaved nucleus?
: the zygote nucleus formed by the fusion of male and female pronuclei.
Can lymphocytes have nucleoli?
Reactive lymphocytes are large, immune-stimulated lymphocytes with dark-blue cytoplasm and irregular, scalloped, or cleaved nuclei. They are also called immunocytes. In contrast, blast-transformed lymphocytes have a large nucleus with light, dispersed chromatin pattern with prominent nucleoli or nucleolar rings.
What are transformed lymphocytes?
… transformed lymphocyte (TL) is defined as a large lymphoid cell that is two to three times the size of a normal lymphocyte, with a vesicular noncleaved nucleus. Nucleoli could be large and prominent or smaller and less distinct (Fig 1).
What kind of lymphoma is a cleaved nucleus?
“Cleaved” lymphocytosis can occur, which refers to the cleft appearing nuclei. Other disorders with angulated or cleaved lymphocytes include pertussis and MCL as above in addition to Sezary Syndrome and Adult T cell lymphoma/leukemia (ATLL).
How big is the nucleus of a lymphocyte?
A lymphocyte may range in size from 7 to 15 µm with variable, typically high N:C ratio. The nucleus in the The nucleus in the current cell shows an unusual deeply cleaved nucleus; however maintains the dense clumped chromatin.
What kind of lymphocytes have a cleft nucleus?
The lymphocytes were polymorphous but many had a cleft nucleus (panels A-F; May-Grünwald-Giemsa stain, original magnification ×100), suggestive of lymphoma (eg, follicular lymphoma or Sézary syndrome). This cytological presentation together with the clinical findings were typical of “malignant whooping cough.”
What are the physical features of reactive lymphocytes?
Morphology of reactive lymphocytes is highly variable from cell to cell. In general, features include: Nucleus – large, reticular chromatin pattern. Nucleoli may be present. Cytoplasm – abundant, light to deep blue. Pale perinuclear zones may be present.