What are the indications of dobutamine?
Dobutamine is indicated for patients who require positive inotropic support in the treatment of cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures, especially when a low cardiac output is associated with raised pulmonary capillary …
What are the contraindications of dobutamine?
The medication is contraindicated in patients with acute myocardial infarction, unstable angina, left main stem disease, severe hypertension, arrhythmias, acute myocarditis or pericarditis, hypokalemia and idiopathic hypertrophic sub-aortic stenosis.
What are the therapeutic effects of dobutamine?
Dobutamine stimulates heart muscle and improves blood flow by helping the heart pump better. Dobutamine is used short-term to treat cardiac decompensation due to weakened heart muscle. Dobutamine is usually given after other heart medicines have been tried without success.
What is the action of dobutamine?
Dobutamine directly stimulates beta-1 receptors of the heart to increase myocardial contractility and stroke volume, resulting in increased cardiac output.
When should you not use dobutamine?
In general, caution should be exercised when administering dobutamine in patients with moderate or severe hypotension (eg, systolic blood pressure <80 mm Hg), because the peripheral vasodilation, in some cases, may cause a further fall in blood pressure.
Why is dobutamine used in cardiogenic shock?
Dobutamine is a catecholamine with β-1 and β-2 adrenergic agonist properties which help improve myocardial contractility. In patients with cardiogenic shock due to decompensated heart failure, dobutamine decreases left ventricular end-diastolic pressure and raises blood pressure by increasing cardiac output.
What are the contraindications of digoxin?
Digoxin is contraindicated in the following conditions[5]:
- Acute myocardial infarction.
- Hypersensitivity to the drug.
- Ventricular fibrillation.
- Myocarditis.
- Hypomagnesemia.
- Hypokalemia.
- Wolf-Parkinson-White syndrome.
What are the major side effects of norepinephrine and dobutamine?
Common side effects of dobutamine include:
- increased heart rate and increased blood pressure,
- ventricular ectopic activity,
- nervousness,
- headache,
- nausea,
- vomiting,
- palpitations,
- low platelet counts (thrombocytopenia), or.
What is the primary pharmacological action of dobutamine?
Dobutamine is a direct-acting inotropic agent whose primary activity results from stimulation of the ß receptors of the heart while producing comparatively mild chronotropic, hypertensive, arrhythmogenic, and vasodilative effects. It does not cause the release of endogenous norepinephrine, as does dopamine.
Is dobutamine contraindicated in hypotension?
Is dobutamine contraindicated in myocardial infarction?
Hemodynamic indices including the cardiac output (CO), pulmonary pressures and pulmonary artery capillary wedge pressure (PAWP) were measured.
Does dobutamine raise BP?
Dobutamine hydrochloride may cause a marked increase in heart rate or blood pressure, especially systolic pressure. Approximately 10% of patients in clinical studies have had rate increases of 30 beats/minute or more, and about 7.5% have had a 50 mm Hg or greater increase in systolic pressure.
What is dobutamine used for?
The medicine Dobutamine is used to treat Low Cardiac Output
What is dobutamine drip?
Dobutamine is used to treat acute but potentially reversible heart failure, such as which occurs during cardiac surgery or in cases of septic or cardiogenic shock, on the basis of its positive inotropic action. Dobutamine can be used in cases of congestive heart failure to increase cardiac output.
What is dopamine drips?
At high doses, Dopamine may help correct low blood pressure due to low systemic vascular resistance. Dopamine is used to treat hypotension (low blood pressure), low cardiac output, and reduced perfusion of body organs due to shock, trauma, and sepsis.