Does nifedipine affect fetus?
Conclusion: The results suggest that, in addition to tocolysis, nifedipine can cause vascular dilatation in both the uterus and the placenta. The use of nifedipine within the normal dose range does not appear to adversely affect fetal outcome and may potentially improve fetal outcome in some disorders of pregnancy.
Is nifedipine safe in second trimester?
Conclusions: The dihydropyridine group of calcium channel blockers (type II calcium blockers) and, specifically, nifedipine are safe for use in pregnancy. They have little teratogenic or fetotoxic potential.
What are the side effects of nifedipine while pregnant?
Other commonly reported side effects of nifedipine are maternal tachycardia, palpitations, flushing, headaches, dizziness, and nausea. Continuous monitoring of the fetal heart rate is recommended as long as the patient has contractions; the patient’s pulse and blood pressure should be carefully monitored.
Is blood pressure high at 16 weeks pregnant?
Some women are found to have high blood pressure before they are 20 weeks pregnant. (If high blood pressure is first discovered before you are 20 weeks pregnant, this usually means that you had previously undetected high blood pressure before you were pregnant.)
Can preterm labor be stopped?
For about 3 in 10 women, preterm labor stops on its own. If it does not stop, treatments may be given to try to delay birth. In some cases, these treatments may reduce the risk of complications if the baby is born.
Can nifedipine cause abortion?
Miscarriage can occur in any pregnancy. Two studies reported a higher number of miscarriages in pregnancies exposed to calcium channel blockers, such as nifedipine, when compared to pregnancies not exposed to calcium channel blockers.
Can labetalol cause birth defects?
Use of labetalol in pregnancy is common and there is no concern that it causes harm. Labetalol belongs to a family of medicines called beta blockers. Studies have not shown that beta blockers cause birth defects, stillbirth, or preterm birth. Women taking beta blockers may be more likely to have a small baby.
How can I reduce the side effects of nifedipine?
Do not eat grapefruit or drink grapefruit juice. This is because grapefruit can make the side effects of nifedipine worse. Otherwise, you can eat and drink normally while taking nifedipine. Eating well can help if you have high blood pressure or heart failure.
Can nifedipine cause fetal tachycardia?
Maternal side effects of nifedipine are uncommon and include flushing, headache, dizziness and sweating of palms 3. Rarely constipation, diarrhea, heartburn, dyspnea and chest pain have been reported. Tachycardia occurs commonly but is seldom associated with palpitation and appears to have no adverse effects.