What is an actinic granuloma?
Actinic granuloma is an uncommon granulomatous disease, characterized by annular erythematous plaque with central clearing predominately located on sun-damaged skin. The pathogenesis is not well understood, ultraviolet radiation is recognized as precipitating factor.
Is actinic granuloma an autoimmune disease?
Actinic granuloma is a rare granulomatous reaction that is more commonly seen in females and thought to occur as an autoimmune response to actinic damage of elastic tissue. We discuss a case of a patient with actinic granuloma presenting with concomitant temporal arteritis.
What kind of cancer is associated with granuloma annulare?
Lesions that mimic granuloma annulare or are histologically confirmed as granuloma annulare have occurred in association with the following: Non-Hodgkin lymphoma. Hodgkin lymphoma. Acute myelogenous leukemia.
What is a foreign body granuloma?
A foreign body granuloma forms when the host immune system is unable to digest the foreign body, resulting in the accumulation of macrophages and histiocytes. As macrophages surround and isolate the foreign body, some of them will fuse to form multinucleated giant cells.
Is granuloma annulare a symptom of cancer?
Granuloma annulare is a benign (not cancer), often chronic (long-lasting) skin disorder in which inflammation in the skin causes a raised, discolored rash or lumps under the skin. In most cases, rashes form on the hands, feet and forearms.
Can a granuloma be cancer?
Are granulomas cancerous? Although granulomas may appear cancerous, they are not — they are benign. Occasionally, however, granulomas are found in people who also have particular cancers, such as skin lymphomas.
What is a calcified granuloma in the lung?
A calcified granuloma is a specific type of tissue inflammation that has become calcified over time. When something is referred to as “calcified,” it means that it contains deposits of the element calcium. Calcium has a tendency to collect in tissue that is healing.
Will granuloma annulare ever go away?
The lesions associated with granuloma annulare usually disappear without treatment (spontaneous remission). However, the lesions often reappear. The exact cause of granuloma annulare is unknown.
Is foreign body granuloma painful?
Foreign body granuloma is a tissue reaction for retained foreign bodies after skin-penetrating trauma. Detection of retained foreign bodies can be extremely difficult when the patients present with non-specific symptoms such as pain and/or swelling without recognizing a previous trauma.
How do I choose the best granuloma annulare treatment?
One option for granuloma annulare treatment cryotherapy, which involves applying liquid nitrogen to any bumps on the skin to freeze them off. Drinking lots of water may help treat granuloma annulare. Corticosteroids applied as a topical ointment are the usually the first choice of treatment by dermatologists for granuloma annulare.
What conditions are associated with granuloma annulare?
Granuloma annulare (GA) is a long-term ( chronic) skin disease consisting of a rash with reddish bumps arranged in a circle or ring. GA most often affects children and young adults. It is slightly more common in females. The condition is usually seen in otherwise healthy people. Sometimes, it may be associated with diabetes or thyroid disease.
What are the possible complications of granuloma annulare?
The complications of Granuloma Annulare are not very significant, but may include the following: Recurrences of the condition after the signs and symptoms disappear are very common In some individuals, they may cause cosmetic disfigurement and stress, since Granuloma Annulare may be a longstanding condition Some scarring may occur, however typically the lesions disappear without leaving any evidence
What causes granuloma annulare skin?
It’s not clear what causes granuloma annulare. Sometimes it’s triggered by: Animal or insect bites. Infections, such as hepatitis. Tuberculin skin tests. Vaccinations. Sun exposure. Minor skin injuries.