What is high alpha-2 globulin?
High alpha-2 globulin: Inflammation; kidney disease. High beta globulin: Very high cholesterol; low iron (iron-deficiency anemia) High gamma globulin: Inflammation; infection; liver disease; some forms of cancer.
What causes increased alpha-2 globulin?
Alpha2 macroglobulin levels may be raised in nephrotic syndrome and haptoglobin levels are increased in stress, infection, inflammation, and tissue necrosis. Haptoglobin levels may be decreased in haemolytic conditions.
What does Alpha globulin do?
Alpha globulins are a group of globular proteins in plasma that are highly mobile in alkaline or electrically charged solutions. They inhibit certain blood proteases and show significant inhibitor activity.
What is Alpha 2 on a blood test?
Alpha-2-macroglobulin is a protease inhibitor and is one of the largest plasma proteins. It transports hormones and enzymes, exhibits effector and inhibitor functions in the development of the lymphatic system, and inhibits components of the complement system and hemostasis system.
What is Alpha 2 in blood work?
Alpha-2 globulins: This class of protein has many functions in the body and is involved in inflammation. Beta globulins: These proteins move substances, support immunity, and increase in number in multiple myeloma and conditions like high cholesterol and atherosclerosis.
What is a normal albumin globulin ratio?
In general, an albumin/globulin ratio between 1.1 and 2.5 is considered normal, although this can vary depending on the laboratory performing the test [4]. Your blood usually contains a little more albumin than globulin, which is why a normal ratio is slightly higher than 1 [1].
What is normal range for globulin?
Normal value ranges are: Serum globulin: 2.0 to 3.5 grams per deciliter (g/dL) or 20 to 35 grams per liter (g/L) IgM component: 75 to 300 milligrams per deciliter (mg/dL) or 750 to 3,000 milligrams per liter (mg/L) IgG component: 650 to 1,850 mg/dL or 6.5 to 18.50 g/L.
What happen if globulin is high?
High levels may indicate infection, inflammatory disease or immune disorders. High globulin levels may also indicate certain types of cancer, such as multiple myeloma, Hodgkin’s disease, or malignant lymphoma. However, abnormal results may be due to certain medications, dehydration, or other factors.
Can high globulin be treated?
Since hypergammaglobulinemia is caused by other conditions, there aren’t many direct treatment options available. But you can improve or cure this condition by treating other underlying infections, immune disorders, and diseases. One uncommon treatment for this condition is immunoglobulin replacement therapy.