What are side effects of cyclosporine?
Common side effects of cyclosporine include:
- High blood pressure.
- Increased hair growth.
- Swollen or inflamed gums.
- Numbness or tingling of the hands or feet.
- Other common side effects are tremors, restlessness, stomach upset, nausea, cramps, diarrhea, headache, and changes in blood sugar.
Do you take cyclosporine with food?
How should I take this medication? Cyclosporine should be taken with food to decrease stomach upset, but may be taken on an empty stomach. Be consistent, if you take it with food, always take it with food; if you take it on an empty stomach, always take it on an empty stomach.
Which is a major adverse effect of cyclosporine?
Shaking, headache, dizziness, unusual growth of body hair, nausea/vomiting, diarrhea, stomach upset, or flushing may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Unusual growth and swelling of the gums may occur.
How do you handle cyclosporine?
Those handling cyclosporine must wear chemically resistant gloves, lab coat, eye protection, and appropriate lab attire (pants, closed-toe shoes). Preparing cyclosporine solutions: 1. Those preparing cyclosporine solutions must always handle it inside a certified chemical fume hood.
What medications can interact with cyclosporine?
What Other Drugs Interact with Cyclosporine?
- amphotericin B deoxycholate.
- atorvastatin.
- bosentan.
- cidofovir.
- elbasvir/grazoprevir.
- flibanserin.
- lomitapide.
- mifepristone.
What medication interacts with cyclosporine?
Cyclosporine may interact with other medications
- Antibiotics. Taking cyclosporine with certain antibiotics may lead to an increased risk of kidney damage.
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Antifungals.
- Acid reflux drugs.
- Birth control drugs.
- Immunity-suppressing drug.
- High cholesterol drugs.
- Blood pressure drugs.
Can cyclosporine cause low platelets?
Other side effects of cyclosporine include: Low white blood cell count (leukopenia) Low platelet count (thrombocytopenia) Severe allergic reaction (anaphylaxis)
Can you take cyclosporine on an empty stomach?
You may take cyclosporine with food or on an empty stomach as long as you take it the same way with each dose. You may be given capsules of more than one strength to make the right dose. Cyclosporine oral solution should be carefully measured and then diluted with liquid (orange juice, apple juice, etc.) before taking.
How do you administer ciclosporin?
3–5 mg/kg daily, to be administered over 2–6 hours from day before transplantation to 2 weeks postoperatively, alternatively (by mouth) initially 12.5–15 mg/kg daily, then (by mouth) 12.5 mg/kg daily for 3-6 months and then tailed off (may take up to a year after transplantation).
Does cyclosporine cause hyponatremia?
In a study comparing cyclosporine and tacrolimus in renal transplant recipients, Higgins et al. [2] showed that hyponatremia and hyperkalemia were more common with tacrolimus compared to cyclosporine.
What special precautions are required when handling cytotoxic medications?
Clear procedures, which staff who handle cytotoxics or contaminated waste should be familiar with, must be in place for dealing with spillages or contamination of people or work surfaces. Measures to prevent or contain spillages should be used at all times. Any spillages that do occur should be dealt with promptly.