Can I change from rosuvastatin to atorvastatin?
Background: Now that generic atorvastatin has become available, a process of switching from rosuvastatin to atorvastatin may occur and could persist until the patent on branded rosuvastatin expires. It is important to understand the impact that such therapy may have on patients’ cardiovascular (CV) health.
What intensity statin is rosuvastatin?
Table 1Statin Dosing and ACC/AHA Classification of Intensity
| Statin | Dosage | |
|---|---|---|
| Low-intensity (LDL-C reduction <30%) | Moderate-intensity (LDL-C reduction 30% to <50%) | |
| Pitavastatin | 1 mg | 2 to 4 mg |
| Pravastatin | 10 to 20 mg | 40 to 80 mg |
| Rosuvastatin | NA | 5 to 10 mg |
Is rosuvastatin 20 high intensity statin?
Atorvastatin 40 or 80 mg and rosuvastatin 20 mg were defined as high‐intensity statins, and the other statins were classified as non‐high‐intensity statins.
What is a moderate to high intensity statin?
Moderate-Intensity Statins. • Atorvastatin 10–20 mg. • Rosuvastatin 5–10 mg. • Simvastatin 20–40 mg. • Pravastatin 40–80 mg.
Is simvastatin 80 high intensity?
High intensity treatment was defined as atorvastatin 40 to 80 mg, rosuvastatin 20 to 40 mg, or simvastatin 80 mg.
What is a moderate to high-intensity statin?
What is the difference between livalo and Crestor?
Livalo (pitavastatin) lowers your cholesterol and prevents heart disease, but may be more expensive than other medicines that work just like it. Lowers cholesterol. Crestor (rosuvastatin) is one of the most effective statins to improve cholesterol. It’s also available as a generic.
Which is an equivalent tablet size for a statin?
Statins (HMG-CoA Reductase Inhibitors) ‘ — ‘ Signifies that equivalent tablet size is not available (comparable dose is either too high or too low) Drug Comparisons – Home Page: Equivalent Dosages -1: Atorvastatin (Lipitor ®): — (see tablet strengths) Fluvastatin (Lescol ®): 20 mg: Lovastatin (Mevacor ®): 10 mg: Pravastatin (Pravachol ®): 10 mg
When to take rosuvastatin 40 mg or 20 mg?
-The 40 mg dose should be reserved for patients who have not achieved their LDL-C goal utilizing the 20 mg dose. -This drug has not been studied in Fredrickson Type I and V dyslipidemias. -Patients should be instructed to read the US FDA-approved patient labeling (Patient Information).
What is the mechanism of action of rosuvastatin?
Rosuvastatin is a HMG-CoA Reductase Inhibitor. The mechanism of action of rosuvastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor. Rosuvastatin is a statin with antilipidemic and potential antineoplastic activities.
Which is the highest intensity statin for LDL-C?
Statin Dose Intensity and Equivalency Chart* Statin Intensity %LDL-C Reduction HMG-CoA Reductase Inhibitor Rosuvastatin Atorvastatin Pitavastatin Simvastatin Lovastatin Pravastatin Fluvastatin High- Intensity (lowers LDL-C ≥ 50%) 63 40 mg ($196)