What does a positive DNA DS antibody mean?
Interpretation. A positive result for double-stranded DNA (dsDNA) IgG antibodies in the appropriate clinical context is suggestive of systemic lupus erythematosus (SLE).
What is considered a high level of anti-dsDNA?
<30.0 IU/mL Negative 30.0 – 75.0 IU/mL Borderline >75.0 IU/mL Positive Negative is considered normal. changes in the levels of these antibodies should not be relied upon to predict changes in clinical course of patients with LE.
What is the normal range DNA DS antibody?
Interpretation: A NORMAL result is < 10 IU/mL (NEGATIVE). An EQUIVOCAL result is 10 – 15 IU/mL. A POSITIVE result is > 15 IU/mL The results obtained by this method should serve as an aid to diagnosis and should not be interpreted as diagnostic in itself.
What is considered a positive dsDNA?
A positive result for double-stranded DNA (dsDNA) IgG antibodies in the appropriate clinical context is suggestive of systemic lupus erythematosus (SLE).
What is ds DNA test?
The anti-dsDNA (anti-double stranded DNA) antibody test is a blood test that looks for antibodies to double stranded DNA. The anti-dsDNA antibody test is a very specific test for Systemic Lupus Erythematosus (SLE) because Anti-dsDNA antibodies aren’t found in any other autoimmune disorders.
What does anti DNA DS AB QN mean?
Optimal Result: 0 – 9 IU/ml. The anti-dsDNA test identifies the presence of these autoantibodies in the blood. The test for anti-dsDNA, along with other autoantibody tests, may be used to help establish a diagnosis of lupus and distinguish it from other autoimmune disorders.
What does a high anti DNA DS AB QN mean?
A high level of anti-dsDNA in the blood is strongly associated with lupus and is often significantly increased during or just prior to a flare-up. When the anti-dsDNA is positive and the person tested has other clinical signs and symptoms associated with lupus, it means that the person tested likely has lupus.
What is lupus disease symptoms?
Joint pain, stiffness and swelling. Butterfly-shaped rash on the face that covers the cheeks and bridge of the nose or rashes elsewhere on the body. Skin lesions that appear or worsen with sun exposure. Fingers and toes that turn white or blue when exposed to cold or during stressful periods.
Why is ds DNA test done?
The anti-double stranded DNA (anti-dsDNA) test is used to help diagnose lupus (systemic lupus erythematosus, SLE) in a person who has a positive result on a test for antinuclear antibody (ANA) and has clinical signs and symptoms that suggest lupus.