What is epithelial hypertrophy?
Epithelial hyperplasias are patterns of epithelial cell increase and are commonly present in breast biopsies. From: Breast Pathology, 2006.
What is the epithelium lining the outer retinal pigmented layer?
The pigmented layer of retina or retinal pigment epithelium (RPE) is the pigmented cell layer just outside the neurosensory retina that nourishes retinal visual cells, and is firmly attached to the underlying choroid and overlying retinal visual cells….
| Retinal pigment epithelium | |
|---|---|
| FMA | 58627 |
| Anatomical terminology |
What are retinal pigment epithelial changes?
As the retinal pigment epithelium (RPE) ages, a number of structural changes occur, including loss of melanin granules, increase in the density of residual bodies, accumulation of lipofuscin, accumulation of basal deposits on or within Bruch’s membrane, formation of drusen (between the basal lamina of the RPE and the …
What is the pigmented layer of the retina?
Retinal pigment epithelium (RPE) is formed from a single layer of regular polygonal cells arranged at the outermost layer of the retina. The outer side of the RPE is connected to Bruch’s membrane and the choroid, while the inner side is connected to the outer segment of photoreceptor cells.
What is retinal pigment epithelium hypertrophy?
The retinal pigment epithelium (RPE) is a pigmented layer of the retina which can be thicker than normal at birth (congenital) or may thicken later in life. Areas of retinal pigment epithelial (RPE) hypertrophy usually do not cause symptoms. They are typically found during routine eye examinations.
What is retinal hypertrophy?
Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is a rare benign lesion of the retina, usually asymptomatic and detected at routine eye examination. It results from a proliferation of pigmented epithelial cells, well defined, flat, does not cause visual symptoms if they do not reach the macula.
What are the 10 layers of the retina?
Broadly there are ten layers in Retina: 1.
- Retinal pigment epithelium 2.
- Layer of Rods & Cones 3.
- External limiting membrane 4.
- Outer nuclear layer 5.
- Outer plexiform layer 6.
- Inner nuclear layer 7.
- Inner plexiform layer 8.
- Ganglion cell layer 9.
What is the outermost layer of the retina?
The outermost layer of the retina, the retinal pigment epithelium, is tightly attached to the choroid. Assuming that the ocular media (cornea, anterior chamber, lens, and vitreous) are not cloudy, the living retina can be examined using a direct or with a high diopter biconvex retinal lens at the slit lamp.
What are the 3 main functions of the cells of the pigmented layer of the retina?
The main functions of the RPE are the following: (1) Transport of nutrients, ions, and water (2) absorption of light and protection against photooxidation, (3) reisomerization of all-trans-retinal into 11-cis-retinal, which is a key element of the visual cycle, (4) phagocytosis of shed photoreceptor membranes, and (5) …
What is the function of the pigmented epithelial layer and the sensory layer of the retina?
The retina consists of two layers: the sensory retina, which contains nerve cells that process visual information and send it to the brain; and the retinal pigment epithelium (RPE), which lies between the sensory retina and the wall of the eye.