Can you get pregnant without classic CAH?
Pregnancies with NC-CAH are thought as high-risk, because of higher rates of miscarriages, predominantly in those who are not covered with GCs (26.3 vs. 6.5%) [6].
Can I get pregnant if I have congenital adrenal hyperplasia?
Women with congenital adrenal hyperplasia (CAH) can suffer from impaired fertility rates as a result of increased androgen secretion or impaired sex steroid production. CAH patients have lower pregnancy rate compared to normal women. Only a few cases with successful pregnancy have been reported in the literature.
Can someone with CAH have children?
With the recommended hormone treatment and close follow-up with a pediatric endocrinologist, children with CAH can grow and develop like other children. In adulthood, most will be able to have children of their own.
How common is non classical CAH?
of non-classical congenital adrenal hyperplasia is approximately 1 in 3 Ashkenazi Jews. In the wider population the carrier frequency is 1 in 100 people. The disease frequency in Ashkenazi Jews is approximately 1 in 27.
Does NCAH cause infertility?
Objective: Nonclassic congenital adrenal hyperplasia (NCAH) is common among Ashkenazi Jews (1:400). It is associated with various degrees of postnatal virilization, irregular menses and infertility. Therapy of symptomatic subjects consists of physiologic doses of glucocorticoids.
Does congenital adrenal hyperplasia cause infertility in men?
In males, congenital adrenal hyperplasia due to 21 hydroxylase deficiency is associated to normal fertility or infertility caused by a hypogonadotrophic hypogonadism (HH) or gonadal damage caused by intratesticular adrenal remnants.
How can I get pregnant with CAH?
Suppression of androgens from the adrenal gland is usually the first therapeutic strategy to achieve spontaneous ovulation and conception. Ovulation induction agents or IVF can be used in CAH patients who are unable to conceive naturally or with anovulatory menstrual cycles despite adequate treatment.
Can CAH be diagnosed prenatally?
CAH is diagnosed prenatally by chorionic villus sampling (CVS) at approximately 14 weeks of gestation, or later, at approximately 20 weeks, by amniocentesis (Figure 1).
Does adrenal hyperplasia affect boy and girl babies both?
Congenital adrenal hyperplasia (CAH) is an inherited disorder of the adrenal glands that can affect both boys and girls.