What does NSAID stand for in medical category?
Other names: anti-inflammatory drugs, nonsteroidal, NSAIDs. Nonsteroidal anti-inflammatory agents (usually abbreviated to NSAIDs) are a group of medicines that relieve pain and fever and reduce inflammation.
How are coxibs and nonselective NSAIDs related to cardiovascular events?
Both nonselective NSAIDs and cyclooxygenase (COX)-2 selective NSAIDs (coxibs) increase the risk of such events. Although the risk of adverse cardiovascular events is heterogeneous across NSAIDs, the precise absolute and relative risk data for many of these agents are limited.
Are there any side effects to taking an NSAID?
Those that favor COX-2 have a higher risk of cardiovascular effects but less gastrointestinal effects. Higher dosages of NSAIDs tend to result in more COX-2 enzyme inhibition (and more cardiovascular side effects), even in those NSAIDs traditionally seen as low risk (such as ibuprofen).
What are the different types of NSAIDs for pain?
Medications & Supplements 1 Ibuprofen vs. Meloxicam (Mobic) for Pain. 2 ibuprofen (Advil, Children’s Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, and others). 3 naproxen (Aleve, Anaprox, Naprelan, Naprosyn). 4 Oxycodone vs. Tramadol for Pain. 5 Aspirin vs. Plavix (clopidogrel). 6 (more items)
What are the side effects of non selective NSAIDs?
Comparison of Non selective and selective NSAIDs Side Effect. A common side effect of using non selective NSAIDs is gastric irritation. This is due to the inhibition of COX-1. The main function of prostaglandins which are synthesized from arachidonic acid by using COX-1 enzyme is to protect the gastric mucosa.
How are the clinical effects of NSAIDs mediated?
Therefore, the clinical effects of NSAIDs are mediated via COX-2 inhibition, whereas COX-1 inhibition is linked to their adverse effect profile (see below). NSAIDs act via reversible inhibition of these enzymes, except aspirin, which acts as a ireversible inhibitor of these enzymes.
What kind of pain can you get from NSAIDs?
NSAIDs are used to treat mild-to-moderate pain that arises from a wide range of conditions such as headaches, menstruation, migraines, osteoarthritis or rheumatoid arthritis, sprains and strains, and toothache.