What is perflutren lipid microspheres injection?
Perflutren lipid microsphere injection is used during an echocardiogram to help diagnose or find problems in the heart. Perflutren lipid microsphere is an ultrasound contrast agent. Ultrasound contrast agents are used to help provide a clear picture during ultrasound.
What type of drug is perflutren?
Perflutren is an ultrasound contrast agent that is used to improve the quality of an echocardiogram (ultrasound of the heart). Perflutren works by changing the way ultrasound waves travel within your heart. This helps the ultrasound portray a sharper image of your heart.
How do you administer DEFINITY?
DEFINITY® may be injected by either an intravenous (IV) bolus or infusion. The maximum dose is either two bolus doses or one single intravenous infusion. The safety of bolus and infusion dosing in combination or in sequence, has not been studied.
What is perflutren lipid microsphere side effects?
Side Effects
- Black, tarry stools.
- chest pain.
- difficulty with breathing.
- dizziness, severe or continuing.
- fast, pounding, or irregular heartbeat or pulse.
- hives, itching, or skin rash.
- lightheadedness when getting up from a lying or sitting position.
- slow or irregular heartbeat.
Does DEFINITY contrast affect kidneys?
Definity® has been approved in the United States for cardiac indications. Extensive studies of these agents have demonstrated a significant safety profile with no evidence of toxicity to the kidneys, heart or liver.
What is DEFINITY injection?
DEFINITY® is an injectable cardiovascular ultrasound enhancement agent comprised of lipid-coated echogenic microbubbles filled with octafluoropropane gas. Administration of DEFINITY® enhances clinicians’ view of the left ventricle of the heart during an echocardiogram to aid with diagnosis.
How do you mix Definity?
Procedure
- Remove cover from the PINSYNC® package.
- Place the activated DEFINITY® vial on a flat surface, hold the PINSYNC® package and push the PINSYNC® vial adapter straight down onto the DEFINITY® vial top until it snaps securely in place.
How do you inject Definity with contrast?
Procedure
- Vent vial with a needle by placing needle tip in the activated DEFINITY® vial.
- Attach an 18 or 20 gauge unfiltered needle to the 3 mL or tuberculin syringe; place needle in the vial.
- Invert vial and slowly withdraw 10 µL/kg activated DEFINITY® from the middle of the liquid. Do not inject air into the vial.
What is Echo optison?
Optison is an ultrasound contrast agent that is used to improve the quality of an echocardiogram (ultrasound of the heart). This medicine works by changing the way ultrasound waves travel within your heart. This helps the ultrasound portray a sharper image of your heart.
What is optison made of?
Each mL of OPTISON contains 5.0-8.0×108 protein-type A microspheres, 10 mg Albumin Human, USP, 0.22 ± 0.11 mg/mL perflutren, 0.2 mg N-acetyltryptophan, and 0.12 mg caprylic acid in 0.9% aqueous sodium chloride.
Is dye injected for echocardiogram?
During the test, a special dye (contrast agent) is injected into your vein to help show structures in the heart better. It allows the inside of the heart to be seen more clearly on the ultrasound pictures.