What is periarticular new bone formation?
Periarticular new bone formation (PNBF) is a well known complication of both spinal and craniocerebral lesions. PNBF is related to the neurological deficit, but its underlying pathophysiology is unclear, and its cause is unknown.
What is remodeling of a joint?
Remodeling of joints is a key feature of inflammatory and degenerative joint disease. Bone erosion, cartilage degeneration and growth of bony spurs termed osteophytes are key features of structural joint pathology in the course of arthritis, which lead to impairment of joint function.
How does bone growth work?
Bone Growth Bones grow in length at the epiphyseal plate by a process that is similar to endochondral ossification. The cartilage in the region of the epiphyseal plate next to the epiphysis continues to grow by mitosis. The chondrocytes, in the region next to the diaphysis, age and degenerate.
What are the 5 stages of bone growth?
30.2A: Stages of Bone Development
- EXAMPLES.
- Initial Bone Formation.
- Intramembranous Ossification.
- Endochondral Ossification.
- Remodeling.
How do bones widen?
IN SUMMARY: Bone Growth and Development Long bones lengthen as chondrocytes divide and secrete hyaline cartilage. Osteoblasts replace cartilage with bone. Appositional growth is the increase in the diameter of bones by the addition of bone tissue at the surface of bones.
Can inflammation cause bone lesions?
The most frequent associated autoimmune and/or inflammatory diseases included arthritis, psoriasis, inflammatory bowel disease, vasculitis, myositis/fasciitis and parotitis. Typically, these patients have more bony lesions than patients without a comorbid inflammatory disease.
What are the stages of bone growth?
The process of bone formation is called osteogenesis or ossification. After progenitor cells form osteoblastic lines, they proceed with three stages of development of cell differentiation, called proliferation, maturation of matrix, and mineralization.