What does DHA reductase do?
Dehydroascorbate reductase (DHAR) is a key enzyme involved in the recycling of ascorbate, which catalyses the glutathione (GSH)-dependent reduction of oxidized ascorbate (dehydroascorbate, DHA). As a result, DHAR regenerates a pool of reduced ascorbate and detoxifies reactive oxygen species (ROS).
What is dehydroascorbic acid used for?
Use. Dehydroascorbic acid has been used as a vitamin C dietary supplement. As a cosmetic ingredient, dehydroascorbic acid is used to enhance the appearance of the skin. It may be used in a process for permanent waving of hair and in a process for sunless tanning of skin.
Which molecule reduces dehydroascorbic acid back to ascorbic acid?
Dehydroascorbic acid may be reduced back sequentially to ascorbate radical and ascorbic acid by glutathione or directly to ascorbic acid by enzyme dependent mechanisms (Linster & Van Schaftingen, 2007).
Is dehydroascorbic acid biologically active?
Dehydroascorbic acid has similar biological activity as ascorbic acid. Both compounds have been shown to have antiviral effects against herpes simplex virus type 1, influenza virus type A and poliovirus type 1 with dehydroascorbic acid having the stronger effect.
What is the function of glutathione peroxidase?
Glutathione peroxidase is an antioxidant enzyme class with the capacity to scavenge free radicals. This is in turn helps to prevent lipid peroxidation and maintain intracellular homeostasis as well as redox balance [71].
What is the structure of dehydroascorbic acid?
C6H6O6
Dehydroascorbic acid/Formula
Is dehydroascorbic acid an antioxidant?
1 Antioxidant vitamins. Vitamin C, including ascorbic acid and dehydroascorbic acid, its oxidation product, has many biological activities in the human body.
What is the chemical formula of Dehydroascorbic acid?
What is the pH of Dehydroascorbic acid?
approximately pH 2
At all temperatures, dehydroascorbic acid has maximum stability at approximately pH 2. The stability decreases at both . higher and lower pH levels.
Is dehydroascorbic acid polar?
Dehydroascorbic acid is an oxidation product of ascorbic acid. Both molecules are very polar, and cannot be retained by reverse-phase mechanism.
Is dehydroascorbic acid soluble in water?
Dehydroascorbic acid is soluble (in water) and a moderately acidic compound (based on its pKa).