What is cutaneous granuloma?
Cutaneous granulomatosis is a heterogeneous group of diseases, characterized by a skin inflammatory reaction triggered by a wide variety of stimuli, including infections, foreign bodies, malignancy, metabolites, and chemicals.
What does granuloma look like?
Granuloma annulare is a rash that often looks like a ring of small pink, purple or skin-coloured bumps. It usually appears on the back of the hands, feet, elbows or ankles. The rash is not usually painful, but it can be slightly itchy. It’s not contagious and usually gets better on its own within a few months.
Can pyogenic granuloma turn into cancer?
They may be lumpy on the surface like a raspberry. Pyogenic granulomas are not contagious and cannot be spread from person to person. They do not turn into cancers and are not usually painful.
What triggers granuloma annulare?
The exact cause of granuloma annulare is unknown (idiopathic). Numerous theories exist linking the cause to trauma, sun exposure, thyroid disease, tuberculosis, and various viral infections.
Are granulomas permanent?
Foreign body granulomas and abscesses due to bovine collagen injections often regress spontaneously within 1–2 years [2–4]. Other types of foreign body granuloma may persist for decades.
Do granulomas go away?
These lumps are called granulomas and can affect how the lungs work. The granulomas generally heal and disappear on their own. But, if they don’t heal, the lung tissue can remain inflamed and become scarred and stiff.
What is cutaneous malignancy?
Cutaneous CS is a tumor with malignant epithelial and mesenchymal differentiation. CS is known by a variety of names, including metaplastic carcinoma, pseudosarcoma, biphasic sarcomatoid carcinoma, and sarcomatous carcinoma.
Can granuloma annulare be cancerous?
Granuloma annulare is a benign (not cancer), often chronic (long-lasting) skin disorder in which inflammation in the skin causes a raised, discolored rash or lumps under the skin. In most cases, rashes form on the hands, feet and forearms.
Is granuloma annulare an autoimmune disorder?
]. In the literature, it has been raised that this association is more than coincidence, and it suggests an autoimmune basis for these conditions (Table 1). 100 patients with generalized granuloma annulare; 13 patients were found to have thyroid disease, while diabetes was diagnosed in 21 patients.
How big is pyogenic granuloma on the skin?
Pyogenic granuloma of the skin presents as a painless red fleshy nodule, typically 5-10mm in diameter, that grows rapidly over a few weeks. The surface is initially smooth but can ulcerate, become crusty, or verrucous.
Which is the most aggressive type of cutaneous melanoma?
It tends to spread more rapidly in depth and is almost always considered invasive (deep) at the time of diagnosis. Nodular melanoma is the most aggressive type of cutaneous melanoma, is more common in males and can occur at any age but is most often seen in individuals aged 60 and older.
Where does melanoma occur on the hands and feet?
The term “acral” defines the location which is of the extremities, namely the skin of the hands and feet, including the nail unit. ALM is the only type of MM which arises equally across all skin types and is frequently observed in darker skin types and represents about half of the melanoma occurring on the hands and feet.
How does a pyogenic granuloma on the lip look?
Pyogenic granuloma easily bleeds with minor trauma. Oral mucosal pyogenic granulomas typically develop on the lip and gums ( gingiva) as pedunculated or sessile slow-growing painless red papules ranging in size from a few millimetres to several centimetres. The surface can be ulcerated with a yellow-fibrinous surface, and easy bleeding.