What is juvenile systemic lupus erythematosus?
Juvenile lupus (also known as juvenile systemic lupus erythematosus or juvenile SLE) is an autoimmune disease in which the body produces antibodies which attack its own cells. This causes inflammation and subsequent damage to multiple organs, including the skin, joints, kidneys, nervous system, heart and lungs.
What is the life expectancy of a child with lupus?
Recent findings: The 5-year survival rate of patients with juvenile-onset systemic lupus erythematosus approaches 100%, and the 10-year survival rate is close to 90%. The development of cumulative organ damage has been observed in 50-60% of patients.
Can a 12 year old have lupus?
Lupus is not a common condition in kids. Systemic lupus has been diagnosed in 5,000 to 10,000 children and teenagers in the United States.
Is there neuropsychiatric involvement in systemic lupus erythematosus ( SLE )?
We are reviewing pathophysiology of neuropsychiatric involvement in systemic lupus erythematosus (SLE) and its therapy. Most of the clinical manifestations of disease are nonspecific complicating the diagnosis, clinical assessment and treatment planning. II. CLINiCAL FEATURES AND EPIDEMIOLOGY
How does CNS lupus affect the nervous system?
CNS lupus can also cause some rare but serious problems, including: Some medicines and other health conditions can cause symptoms similar to CNS lupus. Your doctor can do tests to find out what’s causing your symptoms. Lupus can damage nerves in the body by causing inflammation of the nerves or the tissue around the nerves.
What are the symptoms of Lupus in the brain?
As many as half of all people with lupus describe feelings of confusion, fatigue, memory loss, and difficulty expressing their thoughts. This collection of symptoms is termed cognitive dysfunction, although many people with lupus call it ” lupus fog .”
How is NPSLE treated in the treatment of lupus?
NPSLE manifestations, such as seizures and headaches, should also be treated with a combination of symptomatic and immune-modulating therapy. Seizures are managed with standard anticonvulsants. Although these medications have been implicated in drug-induced lupus, they do not appear to alter idiopathic disease.