What is a Lentiginous junctional melanocytic nevus?
The term lentiginous junctional nevus is used for junctional nevi in which the epidermis has lentigo-like features with elongated and pigmented epidermal rete ridges. In lentiginous nevi, there is typically a proliferation of solitary units and nests.
Is junctional melanocytic nevus cancer?
A junctional nevus is a non-cancerous type of growth made up of melanocytes. Junctional nevi are usually seen in individuals of lighter skin complexion and can be found anywhere on the body.
What is atypical lentiginous nevus?
Atypical lentiginous nevus (of the elderly) is a peculiar form of dysplastic nevus. Clinically, this condition can resemble malignant melanoma and histologically, it has a lentiginous pattern with variable degrees of atypia and an absence of dermal nests.
What is atypical junctional nevus?
Junctional nevi are the result of a single abnormal melanocyte that begins to proliferate at the dermal epidermal junction, and are often seen clinically as a dark flat nevus. A junctional nevus will typically evolve over time into a compound nevus, which is a nevus with both epidermal and dermal melanocytes.
Is lentiginous nevus cancerous?
Background: Atypical lentiginous nevus (of the elderly) is a peculiar form of dysplastic nevus. Clinically, this condition can resemble malignant melanoma and histologically, it has a lentiginous pattern with variable degrees of atypia and an absence of dermal nests.
What is architectural disorder?
The architectural disorder includes asymmetry, subepidermal fibroplasia, and a distorted rete ridge pattern with bridging between adjacent rete rides (see the image below). Compound lesions have extension of the junctional component beyond the dermal nests of melanocytes, referred to as shouldering.
Does melanocytic mean melanoma?
Background Moles, or melanocytic nevi, are both markers of an increased risk of cutaneous melanoma and direct precursor lesions.
Should dysplastic nevus be removed?
Most melanocytes are in the skin, and melanoma can occur on any skin surface. It can develop from a common mole or dysplastic nevus, and it can also develop in an area of apparently normal skin. In addition, melanoma can also develop in the eye, the digestive tract, and other areas of the body.
What is a junctional component?
A, The junctional component is composed of large and expansile melanocytic nests of varying shapes and sizes. B, In areas, a lentiginous growth pattern of atypical melanocytes is observed, and focal Pagetoid spread is present (hematoxylin-eosin, original magnifications 3100 [A] and 3200 [B]).
Can dysplastic nevus become melanoma?
Can a dysplastic nevus turn into melanoma? Yes, but most dysplastic nevi do not turn into melanoma (1, 3). Most remain stable over time.
What does junctional nevus mean?
A junctional nevus is a mole that occurs between two layers of skin. This image shows two junctional nevi that appear as uniformly brown small macules, round in shape with smooth regular borders.