Is Sarcomatoid a cancer?
Sarcomatoid carcinoma, sometimes referred to as pleomorphic carcinoma, is a relatively uncommon form of cancer whose malignant cells have histological, cytological, or molecular properties of both epithelial tumors (“carcinoma”) and mesenchymal tumors (“sarcoma”)….
| Sarcomatoid carcinoma | |
|---|---|
| Specialty | Oncology |
What does Sarcomatoid mean?
Almost any type of renal cell cancer can become sarcomatoid. This means that the cells of the cancer look like the cells of a sarcoma (cancer of the connective tissues, such as muscles, nerves, fat, blood vessels and fibrous tissue).
Are sarcomas painful?
Because sarcoma can develop in flexible, elastic tissues or deep spaces in the body, the tumor can often push normal tissue out of its way as it grows. Therefore, a sarcoma may grow quite large before it causes symptoms. Eventually, it may cause pain as the growing tumor begins to press against nerves and muscles.
What kind of chemotherapy is used for sarcomatoid cancer?
Chemotherapy remains an important treatment modality for patients with sarcomatoid CUP, and 50% of patients received it as their first line of therapy. The most common regimen was gemcitabine and docetaxel, which has been shown to work for epithelial cancers and also sarcoma, followed by a taxane or gemcitabine combination with a platinum agent.
Is there a cure for sarcomatoid carcinoma?
Background: Sarcomatoid carcinoma is a rare, aggressive malignancy containing both mesenchymal and epithelial components. Patients often present with advanced disease and survival is poor. The effectiveness of chemotherapy is unclear.
Can a breast sarcoma be treated with endocrine therapy?
Because sarcoma tumor cells are not ductal breast cells, they do not typically have hormone or HER2 receptors, so endocrine and HER2- targeted therapies are generally not used. Your oncology team will recommend a treatment plan based on what is known about breast sarcomas in general and tailored specifically to your disease.
How are breast sarcomas different from other types of cancer?
Because breast sarcoma cells are more like the connective tissue in the breast than the ductal breast tissue, they act differently than more common kinds of breast cancer. They are often high grade, which means that the cells are very abnormal-looking or dividing rapidly.