Does daptomycin treat Corynebacterium?
Successful treatment of Corynebacterium infections with daptomycin has been reported in the literature, and a number of studies have demonstrated Corynebacterium spp. possessing low MICs to daptomycin in vitro [29-32].
What antibiotic treats Corynebacterium species?
The goal is both to kill the organism and to terminate toxin production. Many antibiotics are effective, including penicillin, erythromycin, clindamycin, rifampin, and tetracycline; erythromycin or penicillin is the treatment of choice and is usually given for 14 days.
How many species of Corynebacterium are there?
The primary pathogen in this group is Corynebacterium diphtheriae, the etiologic agent of diphtheria. Additional corynebacteria include 45 species, 30 of which on rare occasion cause human disease.
What is Corynebacterium infection?
Diphtheria is an infection caused by strains of bacteria called Corynebacterium diphtheriae that make toxin. Diphtheria spreads from person to person, usually through respiratory droplets, like from coughing or sneezing. It can also spread by touching open sores or ulcers of someone with a diphtheria skin infection.
How do you treat Corynebacterium striatum?
striatum infections, in monotherapy or in combination with piperacillin-tazobactam. Alternatively, linezolid, teicoplanin or daptomycin may be used in severe infections, while amoxicillin-clavulanate may be used to treat mild infections caused by C. striatum.
Does doxycycline treat Corynebacterium?
The susceptibilities of 265 strains of Corynebacterium species and other non-spore-forming gram-positive bacilli to 18 antimicrobial agents were tested. Most strains were susceptible to vancomycin, doxycycline, and fusidic acid.
Does ciprofloxacin treat Corynebacterium?
Resistance to beta-lactams, clindamycin, erythromycin, azythromycin, ciprofloxacin and gentamicin was common among strains of Corynebacterium xerosis and Corynebacterium minutissimum.
What is rare Corynebacterium species?
Abstract. Corynebacterium spp. are Gram-positive rods that are recognized to cause opportunistic diseases under certain predisposing clinical conditions. Some species have been described in urinary tract infections.
What are the roles of Corynebacterium in causing disease?
pseudotuberculosis, which causes the disease caseous lymphadenitis, and some are also pathogenic in humans. Some attack healthy hosts, while others tend to attack the immunocompromised. Effects of infection include granulomatous lymphadenopathy, pneumonitis, pharyngitis, skin infections, and endocarditis.
How do you get Corynebacterium species?
Corynebacterium species
- C. pseudotuberculosis: cause of caseous lymphadenitis in goats and sheep; human infection typically derived from contact with infected animals.
- C. ulcerans: infection from handling infected animals or contact with contaminated milk.
Is Corynebacterium striatum serious?
striatum can cause serious infections in immunocompetent hosts, as well6. In addition, cases of patient-to-patient spreading of C. striatum with serious nosocomial outbreaks are described in intensive care units.