Can rosuvastatin cause high CK levels?

Can rosuvastatin cause high CK levels?

A rare but worrisome side effect of taking a cholesterol-lowering statin is the breakdown of muscle tissue. To guard against it, people who take statins have often been advised to have regular blood tests to spot rising levels of creatine kinase (CK), a byproduct of muscle breakdown.

What can cause elevated creatine kinase?

Increased CK may be seen with, for example:

• Recent crush and compression muscle injuries, trauma, burns, and electrocution.
• Inherited myopathies, such as muscular dystrophy.
• Hormonal (endocrine) disorders, such as thyroid disorders, Addison disease or Cushing disease.
• Strenuous exercise.
• Prolonged surgeries.
• Seizures.

Can steroids cause high CK levels?

The findings demonstrated that the increase in serum CK was highest in the subgroup using androgens. These results suggest that strength train- ing with the use of androgenic steroids leads to higher serum CK activities than normal strength training.

What do high CK levels indicate?

CK stands for creatine kinase, an enzyme that leaks out of damaged muscle. When elevated CK levels are found in a blood sample, it usually means muscle is being destroyed by some abnormal process, such as a muscular dystrophy or inflammation.

When should I stop statin CK?

Statin treatment should be discontinued immediately if an elevated CK level is found (i.e. CK >10 x upper limit of normal6), or where myopathy is suspected or diagnosed. If there is a moderate rise in the CK level (i.e. 3-10 x upper limit of normal) then monitor CK levels weekly and seek specialist advice.

How long does it take for CK levels to go down?

Serum CK concentration, mainly the CK-MM subtype, is the most sensitive indicator of damage to muscles. Serum CK begins to rise approximately 2 to 12 hours after the onset of muscle injury, peaks within 24 to 72 hours, and then declines gradually in 7–10 days.

What is a dangerously high CK level?

In rhabdomyolysis, the CK levels can range anywhere from 10 000 to 200 000 or even higher. The higher the CK levels, the greater will be the renal damage and associated complications.

How can I lower my creatine kinase?

Here are 8 ways to naturally lower your creatinine levels.

1. Don’t take supplements containing creatine.
2. Reduce your protein intake.
3. Eat more fiber.
4. Talk with your healthcare provider about how much fluid you should drink.
5. Lower your salt intake.
6. Avoid overusing NSAIDs.
7. Avoid smoking.
8. Limit your alcohol intake.

How can I lower my CK levels?

What drugs raise CK levels?

Prescription drugs and supplements are an important and common cause of CK elevation, so it is important to carefully review medications the patient is taking. Statins can cause myalgia, muscle weakness, and rhabdomyolysis. Up to 5% of users develop CK elevation, typically 2 to 10 times the upper limit of normal.

How do I get my CK levels down?

Can stress increase CK levels?

However, the perception of stress increased and that of recovery decreased in the pre-competitive period. Moreover, CK levels increased soon after the first few weeks of training and tended to remain stable until the pre-competitive phase began, at which time the levels significantly decreased.