What are the ingredients in Januvia?

What is sitagliptin made from?

Sitagliptin Phosphate is the phosphate salt form of sitagliptin, an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis.

Why is januvia bad for you?

The most common side effects of JANUVIA include upper respiratory infection, stuffy or runny nose and sore throat, and headache. JANUVIA may have other side effects, including stomach upset and diarrhea, swelling of the hands or legs, when JANUVIA is used with rosiglitazone (Avandia ®).

What drug can replace Januvia?

Alternatives to Januvia

• linagliptin (Tradjenta)
• metformin (Glucophage, Glucophage XR, Fortamet, Glumetza)
• empagliflozin (Jardiance)
• canagliflozin (Invokana)
• saxagliptin (Onglyza)
• alogliptin (Nesina)
• glipizide (Glucotrol and Glucotrol XL)
• sitagliptin and metformin hydrochloride (Janumet)

Who should not take Januvia?

Who should not take JANUVIA?

• low blood sugar.
• acute inflammation of the pancreas.
• chronic inflammation of the pancreas.
• chronic kidney disease stage 3B (moderate)
• chronic kidney disease stage 4 (severe)
• chronic kidney disease stage 5 (failure)
• kidney disease with likely reduction in kidney function.

  Does Januvia make you pee?

  Does Januvia (sitagliptin) make you urinate more? Januvia (sitagliptin) does not have an effect on how often you urinate like other medications, such as diuretics (water pill).

  Is Januvia safe?

  Overall safety results for Januvia were announced in June 2015 during the American Diabetes Association Scientific Sessions and showed no CV risk among a diverse group of patients taking the drug. A secondary analysis found that the drug did not increase the risk for heart failure among the T2D group.

  Is Januvia a safe drug?

  Is there a cheaper alternative to Januvia?

  Glucophage (metformin) is another possible alternative, and it is likewise affordable; cash prices for metformin average to around $27 per month, and many can even get your prescription for free by shopping around on GoodRx.

  Is Januvia stronger than metformin?

  Although both drugs can cause serious side effects, there are fewer side effects associated with Januvia and the drug is better tolerated than metformin. Januvia is not available in a generic form and is considerably more expensive, while metformin is affordable for most patients.

  Is Januvia bad for the liver?

  Now, a new medical journal “To The Editor” letter suggests that Januvia may have a negative effect on the liver for certain patients, specifically “individuals with a history of nonalcoholic steatohepatitis or elevated hepatic enzymes”.

  Is Januvia a bad drug?

  Heart failure risk The good news is that Januvia has never been linked to heart failure. The bad news is that two other DPP-4 inhibitors have, so the FDA has determined that all DPP-4 inhibitors, including Januvia, should be used cautiously in patients at risk for heart failure.

  What’s the difference between Januvia and Janumet?

  How Januvia and Janumet Work Januvia is the generic drug sitagliptin, while Janumet is a combination of sitagliptin and metformin. Merck developed sitagliptin to control high blood sugar in people with Type 2 diabetes.

  How does Januvia work for type 2 diabetes?

  JANUVIA may help lower your blood sugar (A1C). JANUVIA is a once-daily prescription pill for adults with type 2 diabetes. JANUVIA, along with diet and exercise, helps lower your blood sugar (A1C).

  How much does it cost to get a Januvia prescription?

  JANUVIA helps lower blood sugar along with diet and exercise in adults with type 2 diabetes. Eligible, privately insured patients may save on their out-of-pocket cost on up to 12 qualifying prescriptions. Maximum savings is $150 per prescription.

  Can you take Januvia with or without food?

  You may take Januvia with or without food. Follow your doctor’s instructions. Your blood sugar may need to be checked often, and you may need other blood tests at your doctor’s office. Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink.

  JANUVIA may help lower your blood sugar (A1C). JANUVIA is a once-daily prescription pill for adults with type 2 diabetes. JANUVIA, along with diet and exercise, helps lower your blood sugar (A1C).

  Is there a generic version of Januvia available?

  There is currently no generic version of Januvia. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects 4. Bottom Line

  What are the pros and cons of Januvia?

  No other post has ever generated such ongoing reader energy, both positive and negative. Nearly every day, several new commentors weigh in, duking it out over the relative merits of Januvia. Most everyone seems to agree that Januvia reduces appetite, which is a good thing.

  What is the name of the enzyme that Januvia inhibits?

  These hormones are rapidly inactivated by an enzyme called dipeptidyl peptidase 4 (DPP-4). Januvia belongs to the class of medicines known as DPP-4 inhibitors. It is selective for DPP-4 and does not inhibit DDP-8 or DPP-9 (the inhibition of these two enzymes has been associated with severe toxicity). 2. Upsides