What would happen if you increase the pH of the intermembrane space of the mitochondria?
The pH of the intermembrane space would increase, the pH gradient would decrease, and ATP synthesis would stop.
Would there be a higher pH in the intermembrane space of mitochondrial matrix?
-There must be no difference in pH between the mitochondrial matrix and the intermembrane space. The pH of the intermembrane space must be lower than the pH of the mitochondrial matrix.
Why does the mitochondrial matrix have a higher pH than the intermembrane space?
The ATP formation is driven by H+ flowing down its concentration gradient, which means that the outside concentration of H+ has to be higher than the matrix in order for that to occur. Thus, higher H+ outside constitutes lower (acidic) pH in comparison to the more basic matrix because of ETC activities.
Does the pH of the mitochondrial matrix increase?
Recently, we proposed that the mitochondrial matrix pH contributes to the control of mitochondrial ATP synthesis in β cells. This concept is based on our findings that matrix pH is low in the resting β cell (pH 7.25) and increases to pH 7.7 following stimulation with nutrient secretagogues (10).
What happens to the pH of the intermembrane space and the matrix during oxidative phosphorylation?
In oxidative phosphorylation, the pH gradient formed by the electron transport chain is used by ATP synthase to form ATP. The pH of the intermembrane space would increase, the pH gradient would decrease, and ATP synthesis would stop.
How does pH affect mitochondria?
Low pH increases the concentration of base causing mitochondria to pump out H+ to the inter membrane space leading to ATP production. The high external acid concentration causes an increase in H+ in the inter membrane space leading to increased ATP production by ATP synthetase.
Which side of the inner mitochondrial has a higher pH?
Which side of the inner mitochondrial membrane would have a higher pH? The side of the inner mitochondrial membrane that would have a higher pH would be the inner membrane because it has a low number of hydrogen ions.
How will the binding of cyanide change the pH of the mitochondrial matrix and the pH of the intermembrane space?
Cyanide inhibits cytochrome c oxidase, a component of the electron transport chain. After cyanide poisoning, the electron transport chain can no longer pump electrons into the intermembrane space. The pH of the intermembrane space would increase, the pH gradient would decrease, and ATP synthesis would stop.
Which side of the inner mitochondrial membrane would have a higher pH explain?
Which part of the mitochondria has a higher pH?
1. It generates a pH gradient across the inner mitochondrial membrane, with the pH higher in the matrix than in the cytosol, where the pH is generally close to 7. (Since small molecules equilibrate freely across the outer membrane of the mitochondrion, the pH in the intermembrane space is the same as in the cytosol.)
Why is mitochondrial matrix acidic?
Which part of the mitochondria is more acidic due to the electron transport chain? – Quora. Higher proton concentration means more acidic. Thus the space between the two membranes, where the protons are concentrated by the electron transport system would be the most acidic.
What is the pH of mitochondrial matrix?
about 7.8
Mitochondrial matrix has a pH of about 7.8, which is higher than the pH of the intermembrane space of the mitochondria, which is around 7.0–7.4.