What is triple quadrupole mass spectrometry used for?

What is triple quadrupole mass spectrometry used for?

Applications. The triple quadrupole mass spectrometer allows for increased sensitivity and specificity yielding lower detection and quantitation limits. For these reasons, employment of the TQMS is a vital asset in the fields of drug metabolism, pharmacokinetics, environmental studies, and biological analyses.

How does a triple quadrupole work?

A triple-quadrupole mass spectrometer, also known as QqQ, is a tandem MS method in which the first and third quadrupoles act as mass filters and the second causes fragmentation of the analyte through interaction with a collision gas—it is a radiofrequency-only quadrupole, and can be used in either SIM or scan mode.

What is Triple TOF?

The TripleTOF 5600+ System delivers nominal mass and accurate mass benefits in a single platform. It uniquely integrates comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation workflows. Learn more.

What is spectrometer used for?

A spectrometer is a device for measuring wavelengths of light over a wide range of the electromagnetic spectrum. It is widely used for spectroscopic analysis of sample materials. The incident light from the light source can be transmitted, absorbed or reflected through the sample.

How do ion traps work?

The ion trap functions as a mass spectrometer when the trapping field is changed, so that the trajectories of simultaneously trapped ions of consecutive specific mass/charge ratio become sequentially unstable, and ions leave the trapping field in order of mass/charge ratio.

What is a Qtof?

Q-TOF mass spectrometers combine TOF and quadrupole instruments, a pairing that results in high mass accuracy for precursor and product ions, strong quantitation capability, and fragmentation experiment applicability.

What is the difference between spectrometer and spectrophotometer?

The spectrometer is the part of the spectrophotometer that is most responsible for measuring things. The spectrophotometer is a complete system that includes a light source along with a means to collect the light that has interacted with the things being tested, as well as a spectrometer for measurements.

Are spectroscopy and spectrophotometer the same thing?

Spectroscopy is the measurement of light (IR, Visible, UV, X-ray ). Spectrometry is measuring things that are not light (like ions in mass spectroscopy). A spectrophotometer is a device that is used to measure the intensity of electromagnetic radiation at various wavelengths.

Which is the triple quadrupole LC-MS / MS system?

Shimadzu’s triple quad LC-MS/MS instruments offer superior performance and sensitivity to meet the demands of high-level quantitative analysis including pesticide screening, drug-of-abuse testing, environmental monitoring and biomarker evaluation. Click here to compare Shimadzu’s triple quadrupole LC-MS/MS systems.

What can you do with triple quad system?

Triple Quad 4500 System. The Triple Quad 4500 System takes the API 4000™ LC-MS/MS and intelligently re-engineers it to set a new benchmark for reliable quantitation. It is designed for food, environmental, forensics and clinical research.

What does triple quad 4500 LC-MS / MS do?

With this LC-MS/MS system, you have the sensitivity and performance to meet analytical and regulatory demands for low level trace detection with ease. The Triple Quad 4500 System takes the API 4000™ platform and intelligently re-engineers it to set a new benchmark for reliable quantitation.

What makes the triple quad 6500 so good?

Triple Quad 6500+ LC-MS/MS system features multi-component IonDrive Technology that pushes the boundaries of quantitation. The sensitivity, speed, and performance delivered through these technology enhancements enable you to see it all, from low mass to high mass compounds.