What is the meaning of biological reference interval?
In health-related fields, a reference range or reference interval is the range or the interval of values that is deemed normal for a physiologic measurement in healthy persons (for example, the amount of creatinine in the blood, or the partial pressure of oxygen).
What is meant by biological reference?
A basis of value established for the measure of quantity, weight, extent or quality, e.g. Weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
What does interval mean in health?
interval. [in´ter-val] the space between two objects or parts; the lapse of time between two events. AA interval the interval between two consecutive atrial stimuli. atrioventricular interval (AV interval)
What is a reference interval study?
Reference intervals are essential for clinical laboratory test interpretation and patient care. The study used data collected retrospectively for 5 analytes without exclusions and filtering from a nationwide chain of clinical reference laboratories in the United States.
What is biological reference interval for pregnancy?
3.3. Reference Values for Thyroid Hormones
| Reference range | ||
|---|---|---|
| 1st trimester | ||
| TSHa IU/mL | 141 | 0.05–2.53 |
| free T3b pg/mL (pmol/L) | 141 | 1.54–5.22 (2.37–8.02) |
| free T4c ng/dL (pmol/L) | 139 | 0.95–1.53 (12.23–19.69) |
What are biological reference materials?
WHO biological reference materials are often in limited supply, and only distributed to qualified laboratories. These include National Control Laboratories and manufacturers of biological medicinal products. The materials are distributed through custodians, which are generally one of the WHO Collaborating Centers.
What is reference interval on lab results?
The reference interval for many laboratory tests is defined by threshold values between which the test results of a specified percentage (usually 95%) of apparently healthy individuals would fall.
What is interval example?
An interval scale is one where there is order and the difference between two values is meaningful. Examples of interval variables include: temperature (Farenheit), temperature (Celcius), pH, SAT score (200-800), credit score (300-850).
What are reference intervals used for?
Reference intervals are the most common decision support tool used for interpretation of numerical pathology reports. As laboratory results may be interpreted by comparison with these intervals, the quality of the reference intervals can play as large a role in result interpretation as the quality of the result itself.
What is the normal value of TSH in pregnancy?
TSH levels during pregnancy
| Stage of pregnancy | Normal | Low |
|---|---|---|
| First trimester | 0.6–3.4 mU/L | < 0.6 mU/L |
| Second trimester | 0.37–3.6 mU/L | < 0.3 mU/L |
| Third trimester | 0.38–4.0 mU/L | < 0.3 mU/L |