What is the endochondral ossification process?
Endochondral ossification involves the replacement of hyaline cartilage with bony tissue. Most of the bones of the skeleton are formed in this manner. These bones are called endochondral bones. In this process, the future bones are first formed as hyaline cartilage models. This forms a primary ossification center.
What is Intramembranous and endochondral ossification?
Ossification is the process of bone formation by osteoblasts. Intramembranous ossification is the process of bone development from fibrous membranes. Endochondral ossification is the process of bone development from hyaline cartilage. Long bones lengthen as chondrocytes divide and secrete hyaline cartilage.
Where does intramembranous ossification occur?
bones
The direct conversion of mesenchymal tissue into bone is called intramembranous ossification. This process occurs primarily in the bones of the skull. In other cases, the mesenchymal cells differentiate into cartilage, and this cartilage is later replaced by bone.
What are the 7 steps of endochondral ossification?
Terms in this set (7)
- enlargement of cartilage in chondrocytes.
- blood vessels grow into shaft.
- fibroblasts migrate to bone center and differentiate into osteoblasts.
- bone enlarges.
- centers of epiphysis calcify.
- epiphysis fills with spongy bone.
- during puberty: cartilage production slows while osteoblast activity increases.
What is endochondral ossification and when does it occur?
Endochondral ossification is the process by which bone tissue is formed in early fetal development. It begins when MSCs start to produce a cartilage template of long bones, such as the femur and the tibia, upon which bone morphogenesis occurs.
What’s the difference between Intramembranous and Endochondral?
In intramembranous ossification, bone develops directly from sheets of mesenchymal connective tissue. In endochondral ossification, bone develops by replacing hyaline cartilage.
Where does endochondral lengthening occur?
Both endochondral and perichondral bone growth both take place toward epiphyses and joints. In the bone lengthening process during endochondral ossification depends on the growth of epiphyseal cartilage. When the epiphyseal line has been closed, the bone will not increase in length.