What is kindling in medical terms?
Kindling refers to the phenomenon of increasingly severe withdrawal symptoms, including an increased risk of seizures, that occurs as a result of repeated withdrawal from alcohol or other sedative–hypnotics with related modes of action.
What happens to an alcoholic’s body?
Alcohol puts the brakes on your immune system. Your body can’t make the numbers of white blood cells it needs to fight germs. So for 24 hours after drinking, you’re more likely to get sick. Long-term, heavy drinkers are much more likely to get illnesses like pneumonia and tuberculosis.
How does addiction get worse?
What makes addiction grow worse? Many people metabolize drugs in different ways. Some people, for example, do not require much alcohol to reach the point of intoxication. Others can seemingly drink vast quantities without feeling intoxicated.
What is kindling in epilepsy?
Kindling is the process by which repeatedly induced seizures result in an increasing seizure duration and en- hanced behavioral involvement of those induced seizures until a plateau is reached.
What is amygdala kindling?
Amygdala kindling is a model of temporal lobe epilepsy (TLE) with convulsion. The rapid amygdala kindling has an advantage on quick development of motor seizures and for antiepileptic drugs screening.
How does alcohol affect the liver?
If you drink large amounts, your liver starts to have a hard time processing the alcohol. If your liver cells are worked too hard, they can start to become damaged. This damage can lead to fatty liver or fibrosis (scarring of the liver) and sometimes cirrhosis (serious liver damage).
What is the strongest Benzo for anxiety?
Alprazolam is the only high-potency benzodiazepine developed in an XR formulation. The efficacy of alprazolam XR 1 to 10 mg using a flexible-dose study design once daily in the treatment of panic disorder was established in two 6-week placebo-controlled studies.
How does benzodiazepines affect the brain?
Benzodiazepines function to increase the levels of gamma amino-butyric acid (GABA) in the brain, which works as a kind of naturally occurring tranquilizer, calming down nerve firings related to stress and the stress reaction.