Does Ehlers-Danlos syndrome affect the immune system?
People with Ehlers-Danlos Syndrome (EDSers) may have higher risk for infections. Fragile skin and poor healing may lead to skin infections. EDSers often have a lowered immune system, possibly due to chronic stress on multiple body systems or an IgG-3 deficiency.
What serious health problems can come with EDS?
There are many neurological and spinal problems which have been observed to be more common in EDS, examples include migraine, early disc degeneration, Chiari 1 malformation, craniocervical instability, motor delay, and curvature of the spine. Musculoskeletal pain can start early and be chronic.
Is Ehlers Danlos type 3 Progressive?
EDS is a slowly progressive disease. EDS symptoms vary by type and range from mildly loose joints to life-threatening complications.
What makes Ehlers Danlos syndrome a Type 3 disorder?
Ehlers-Danlos syndrome, type 3. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele.
Is the treatment for HSD the same as Ehlers Danlos?
Management advice for both hEDS and HSD is the same. Dr Kazkaz talks about the history of the Ehlers-Danlos syndromes, right up to the most recent 2017 reclassification. The genetics behind connective tissue, heritable disorders of connective tissue and the different types of EDS.
Is there a genetic cause for hypermobile Ehlers Danlos?
Although hypermobile Ehlers-Danlos syndrome is regarded as a genetic condition, the underlying cause ( gene or genes responsible) has not been identified. [1] [7] Although the underlying genetic cause of hypermobile Ehlers-Danlos syndrome is unknown, it appears to follow an autosomal dominant pattern of inheritance. [1]
What is the inheritance pattern of Ehlers Danlos?
The inheritance pattern of Ehlers-Danlos syndromes (EDS) varies by subtype. The arthrochalasia EDS, classical EDS, hypermobile EDS, periodontal EDS, some cases of myopatic EDS, and vascular forms of EDS usually have an autosomal dominant pattern of inheritance.
https://www.youtube.com/watch?v=Au5GillheDM