Does atropine cause muscle paralysis?
Atropine will not act on the neuromuscular junction and has no effect on muscle paralysis or weakness, fasciculations or tremors. Atropine is not dependable in reversing the weakness or paralysis of the respiratory muscles.
What is the antidote of atropine?
The antidote to atropine is physostigmine or pilocarpine.
How long does DuoDote last?
The Cmax, Tmax and T½ of pralidoxime following 600 mg pralidoxime given intramuscularly by DuoDote® delivery system was 7 ± 3 mcg/mL, 28 ± 15 minutes, and 2 ± 1 hour, respectively.
Which of the following are side effects that may occur with atropine?
The most common side effects of Atropine include:
- dry mouth,
- blurred vision,
- sensitivity to light,
- lack of sweating,
- dizziness,
- nausea,
- loss of balance,
- hypersensitivity reactions (skin rash), and.
Does atropine cause hypertension?
However, when given by itself, atropine does not exert a striking or uniform effect on blood vessels or blood pressure. Systemic doses slightly raise systolic and lower diastolic pressures and can produce significant postural hypotension.
Does atropine increase heart rate?
Atropine increases the heart rate and improves the atrioventricular conduction by blocking the parasympathetic influences on the heart.
Where does atropine work in the heart?
Atropine increases the firing of the sinoatrial node (atria) and conduction through the atrioventricular node (AV) of the heart by blocking the action of the vagus nerve.
What do you need to know about ATNAA injection?
ATNAA Description. The Antidote Treatment – Nerve Agent, Auto-Injector (ATNAA) provides Atropine Injection and Pralidoxime Chloride Injection in separate chambers as sterile, pyrogen-free solutions for intramuscular injection.
Are there any contraindications for the use of ATNAA?
In the face of life-threatening poisoning by organophosphorous nerve agents, there are no absolute contraindications for the use of the ATNAA (see WARNINGS ).
When to use ATNAA for organophosphorous poisoning?
The ATNAA is indicated for the treatment of poisoning by susceptible organophosphorous nerve agents having anticholinesterase activity. In the face of life-threatening poisoning by organophosphorous nerve agents, there are no absolute contraindications for the use of the ATNAA (see WARNINGS ).
When do you need a hypothermia blanket for ATNAA?
Supportive treatment should be administered as indicated. If respiration is depressed, artificial respiration with oxygen is necessary. Ice bags, alcohol sponges or a hypothermia blanket may be required to reduce fever, especially in children. Catheterization may be necessary if urinary retention occurs.
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