What is heppar1?
Hep par-1: a novel immunohistochemical marker for differentiating hepatocellular carcinoma from metastatic carcinoma.
What is well differentiated hepatocellular carcinoma?
Well-differentiated HCC is defined by the presence of malignant cells that resemble normal hepatocytes with minimal nuclear atypia and the absence of naked nuclei in the smears, that is, the plasma membrane of the neoplastic hepatocytes can survive the force of smearing.
What is CDX2 positive?
These results suggest that positive CDX2 staining represents a highly sensitive and specific marker of metastatic colorectal carcinoma in both biopsy and resected specimens, and is superior to staining for the CK7-/20+ phenotype.
What is the life expectancy of a person with hepatocellular carcinoma?
Unfortunately, HCC is typically diagnosed late in its course, with a median survival following diagnosis of approximately 6 to 20 months. In the United States, 2 years survival is less than 50% and 5-year survival is only 10%.
Is hepatocellular carcinoma curable?
If caught early, it can sometimes be cured with surgery or transplant. In more advanced cases it can’t be cured, but treatment and support can help you live longer and better.
Is TTF-1 positive good or bad?
In this study, we demonstrated that TTF-1 expression was a good prognostic indicator for OS and PFS in patients with stage IV lung adenocarcinoma regardless of the presence or absence of EGFR mutations. We also confirmed that TTF-1 positivity was strongly correlated with EGFR mutations.
Does hepatocellular carcinoma spread quickly?
Liver cancer can spread quickly depending on the type of cancer. Hemangiosarcoma and angiosarcoma types of liver cancer are fast spreading, whereas hepatocellular carcinoma spreads late in the disease.
Is hepatocellular carcinoma a death sentence?
Hepatocellular carcinoma (HCC) is a complex disease and a major cause of death in high endemic areas of hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. HCC has gone from being a universal death sentence to a cancer that can be prevented, detected at an early stage and effectively treated.