What is rifampicin isoniazid pyrazinamide ethambutol HCI?

What is rifampicin isoniazid pyrazinamide ethambutol HCI?

Quadmax is a 4-drug fixed-dose combination (FDC) of antituberculosis drugs rifampicin, isoniazid, pyrazinamide and ethambutol HCl developed as per the recommendations of World Health Organization (WHO), which offers the ease of administration and facilitates patient compliance in the treatment of tuberculosis. Action.

How do you take rifampicin isoniazid pyrazinamide ethambutol hydrochloride tablets IP?

Take this medicine on an empty stomach, at least 1 hour before or 2 hours after a meal. Take each dose with a full glass of water. Your doctor may perform tests to make sure your tuberculosis is not resistant to this medicine. You may also need frequent eye examinations to check your vision.

What is the most common side effect of rifampin?

Upset stomach, heartburn, nausea, menstrual changes, or headache may occur. If any of these effects persist or worsen, inform your doctor promptly. This medication may cause urine, sweat, saliva, or tears to change color (yellow, orange, red, or brown).

What are the contraindications of rifampicin?

Who should not take RIFAMPIN?

  • diabetes.
  • porphyria.
  • decreased blood-clotting from low vitamin K.
  • alcoholism.
  • liver problems.
  • abnormal liver function tests.
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice.

What is the best time to take rifampin?

Rifampin works best on an empty stomach; take it 1 hour before or at least 2 hours after a meal. If you have difficulty swallowing the capsule, you may empty its contents into applesauce or jelly. Take rifampin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

How do you drink Fixcom 2?

The tablets should be taken one hour before or two hours after meals.

  1. Fixcom 2: The dosage schedule will follow the recommended WHO TB treatment regimens.
  2. Patients <55 kg: 3 tabs/day.
  3. Patients 55-70 kg: 4 tabs/day.
  4. Patients >70 kg: 5 tabs/day.

What are the indications of rifampicin?

Indication :

  • Tuberculosis.
  • Staphylococcal infections.
  • Meningococcal Infection prophylaxis.
  • H influenza prophylaxis (off-label)
  • Cholestasis – pruritus.

What are the side effects of isoniazid and rifampicin?

Common side effects may include:

  • red-orange coloration of tears, sweat, saliva, urine, or stools;
  • numbness, tingling, itching, mild rash;
  • drowsiness, dizziness, headache;
  • muscle pain or weakness;
  • heartburn, gas, diarrhea; or.
  • mouth pain.

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