What is free metanephrines test?
The plasma free metanephrines test is used to help diagnose or rule out the presence of a rare tumor called a pheochromocytoma or a paraganglioma (PPGL) that releases excess metanephrines. Testing also may be used when a tumor has been treated or removed to monitor for recurrence.
What is normal range for Metanephrine free?
12 to 60 pg/mL
Normal findings are: Normetanephrine: 18 to 111 pg/mL. Metanephrine: 12 to 60 pg/mL.
What is a Metanephrine blood test?
The test measures the level of a substance called free metanephrine in your blood to find out if your body is producing too much adrenaline or noradrenaline. This can be caused by a condition called phaeochromocytoma – a tumour on the adrenal glands which is usually non- cancerous (benign).
How do you prepare for a metanephrines test?
Patient Preparation Patient should be fasting overnight (water and non-caffeinated soft drinks are permissible). Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection. See Limitations section for more information about other potential causes of elevated metanephrines.
What causes high Metanephrines in urine?
Certain medicines, foods, and conditions can cause metanephrine and catecholamine levels to be higher than normal. These include: Antidepressants and amphetamines. Physical or emotional stress.
What is metanephrine in urine?
Metanephrine and normetanephrine are breakdown products (metabolites) of the catecholamines epinephrine (adrenaline) and norepinephrine. This test measures the amounts of metanephrine and normetanephrine that are released into the urine over a 24-hour period.
What is Metanephrine free?
The plasma free metanephrines test is used to help diagnose or rule out the presence of a rare tumor called a pheochromocytoma or a paraganglioma (PPGL) that releases excess metanephrines. Urine testing measures the total amount of metanephrines released into the urine in 24 hours.
What should I avoid before a Metanephrine test?
Certain foods can increase urinary catecholamines, including coffee, tea, bananas, chocolate, cocoa, citrus fruits, and vanilla. Avoid these for several days prior to the test. Acute stress and vigorous exercise may also affect the test results.
How long do metanephrines stay in your system?
This is because the hormones do not stay long in the blood. They are used by the body and rapidly broken down (metabolized) and/or then eliminated. Urine testing measures the total amount of metanephrines released into the urine in 24 hours.
What are normal Metanephrine levels in urine?
The following normal values are the amount of the substance found in the urine over a 24-hour period: Dopamine: 65 to 400 micrograms (mcg)/24 hours (420 to 2612 nmol/24 hours) Epinephrine: 0.5 to 20 mcg/24 hours. Metanephrine: 24 to 96 mcg/24 hours (some laboratories give the range as 140 to 785 mcg/24 hours)