What is conjunctival intraepithelial neoplasia?
Background: Conjunctival intraepithelial neoplasia (CIN) is the most common tumor of the ocular surface and is a precursor to invasive squamous cell carcinoma. CIN comprises a spectrum of premalignant epithelial neoplasia that usually begins near the limbus and spreads to the cornea.
Is conjunctival intraepithelial neoplasia malignant?
Conjunctival intraepithelial neoplasia (CIN) is the most common conjunctival malignancy in the United States. It occurs in exposed areas of the bulbar conjunctiva with frequent involvement of the adjacent corneal epithelium.
What causes conjunctival intraepithelial neoplasia?
The main causes and associations of CIN in the literature are sun exposure and distance from the equator; human papillomavirus infection, increased p53 expression, and HIV seropositivity.
What is CIN ophthalmology?
CIN is an abnormal line of conjunctival (and possibly corneal) epithelial cells and represents either simple dysplasia (partial thickness of epithelial tissue) or carcinoma in situ when the lesion is full thickness.
What is ocular neoplasia?
Eye neoplasms can affect all parts of the eye, and can be a benign tumor or a malignant tumor (cancer). Eye cancers can be primary (starts within the eye) or metastatic cancer (spread to the eye from another organ). The two most common cancers that spread to the eye from another organ are breast cancer and lung cancer.
Can pterygium be cancerous?
Importantly, pterygia are not cancerous – they are benign growths. That means that while they may grow locally (and possibly affect your sight), they won’t spread to other parts of your body.
Can pterygium become cancerous?
And while pterygia themselves are not cancerous, new findings published by Australian researchers suggest that people who have a pterygium are nearly 25% more likely to develop malignant melanoma – a fatal form of skin cancer.
Can pterygium be malignant?
Pterygium are benign (not malignant) tumors. Hence pterygium do not invade the eye, sinuses or brain. Pterygium do not spread to other parts of the body (metastasize).
What is a conjunctival tumor?
Corneal and conjunctival tumors are malignant cancers that grow on the outer surface of the eye. The most common types of malignant conjunctival tumors are squamous cell carcinoma, malignant melanoma, and lymphoma.
Are eye tumors serious?
Retinal nerve cells begin to grow and multiply, then usually spread into the eye and possibly to other parts of the body. If you have any of the risk factors associated with developing cancer of the eye, you should see an ophthalmologist each year for a thorough examination.
Does pterygium cause blindness?
How serious is it? A pterygium can lead to severe scarring on your cornea, but this is rare. Scarring on the cornea needs to be treated because it can cause vision loss. For minor cases, treatment usually involves eye drops or ointment to treat inflammation.