What are the benefits of vinpocetine?
It was developed in Europe as a drug but sold in the United States as a dietary supplement to improve brain function. Vinpocetine was shown to increase blood flow to the brain and has been studied as a treatment for Alzheimer’s disease and for disorders of the nervous and circulatory systems.
Is vinpocetine good for memory?
Vinpocetine is a partially synthesized supplement created from vincamine, which is derived from the seeds of the periwinkle plant. Though evidence of its cognitive benefits is mixed, it can potentially improve memory and increase brain blood flow and metabolism.
Does vinpocetine increase dopamine?
Vinpocetine is a nootropic phosphodiesterase-1 (PDE-1) inhibitor that acts as an indirect dopamine D1 receptor agonist [12]. Vinpocetine pre-treatment revealed a marked amendment in the hyperlocomotion, anxiety, and short-term memory deficits in schizophrenia patients [13].
What does vinpocetine do for the brain?
Vinpocetine is used to enhance memory and increase brain metabolism. It has also been used for ischemia and reperfusion injury, and is considered a neuroprotective agent. However, there are few robust clinical studies to support the use of vinpocetine in stroke, dementia, or other diseases of the CNS.
Is vinpocetine FDA approved?
Vinpocetine is not approved for any therapeutic use in the United States. The FDA has tentatively ruled that vinpocetine, due to its synthetic nature and proposed therapeutic uses, is ineligible to be marketed as dietary supplement under the Federal Food, Drug, and Cosmetic Act.
How long can you take vinpocetine?
Dosing. The following doses have been studied in scientific research: BY MOUTH: Diseases, such as Alzheimer disease, that interfere with thinking (dementia): 5-10 mg of vinpocetine three times daily for up to 4 months.
Can vinpocetine cause insomnia?
Side effects of vinpocetine may include indigestion, nausea, dizziness, anxiety, facial flushing, insomnia, headache, drowsiness, slower blood clotting, and a temporary drop in blood pressure, according to WebMD. Rigorous, long-term safety research in humans is lacking.
How long can I take vinpocetine?
Does vinpocetine cross the blood brain barrier?
Vinpocetine can pass the blood-brain barrier and enter the brain after oral or intravenous administration (Gulyas et al., 2002a, Gulyas et al., 2002b).
Is vinpocetine a vasodilator?
In the brain, vinpocetine improves brain blood flow by acting as a cerebral vasodilator (Bonoczk et al., 2000, Bonoczk et al., 2002, Patyar et al., 2011, Szilagyi et al., Vas et al., 2002, Zhang and Yang, 2015); and enhances cerebral metabolism by increasing oxygen and glucose uptake and stimulating neuronal ATP …
Does vinpocetine med help with tinnitus?
And research does indicate that vinpocetine might be effective against tinnitus, so it’s a good addition to Clarity2. Vitamin B12 is another ingredient that is included in many health supplements. It’s essential for the development and proper functioning of many different parts of the body, particularly the brain.
Is vinpocetine safe?
When taken by mouth: Vinpocetine is POSSIBLY SAFE for most people when taken by mouth appropriately, short-term. Vinpocetine can cause some side effects including stomach pain, nausea, sleep disturbances, headache, dizziness, nervousness, and flushing of the face.
What is vinpocetine used for?
Vinpocetine is used to enhance memory and increase brain metabolism. It has also been used for ischemia and reperfusion injury , and is considered a neuroprotective agent.