Which are the drugs for 1st line treatment of hypertension?
Practice Pointers. The strongest body of evidence indicates that for most patients with hypertension, thiazide diuretics are the best proven first-line treatment in reducing morbidity and mortality.
What is the best calcium channel blocker for hypertension?
The dihydropyridine calcium channel blockers, a group that includes amlodipine, felodipine and lacidipine, are a common choice for treatment of hypertension. Amlodipine, which is both low cost and taken once daily, is the one of the most commonly prescribed agents.
Are calcium channel blockers first line?
In all actual clinical guidelines, dihydropyridine calcium channel blockers (CCBs) belong to the recommended first line antihypertensive drugs to treat essential hypertension.
Why is ACE inhibitor the first line for hypertension?
ACE (angiotensin-converting enzyme) inhibitors and angiotensin receptor blockers (ARBs) effectively lower blood pressure (BP) through inhibition of the renin-angiotensin system and are equally recommended as first-line medications in the treatment of hypertension.
What is the initial treatment for stage 1 hypertension?
Initial first-line therapy for stage 1 hypertension includes thiazide diuretics, CCBs, and ACE inhibitors or ARBs. Two first-line drugs of different classes are recommended with stage 2 hypertension and average BP of 20/10 mm Hg above the BP target.
Which is better diltiazem or amlodipine?
Although both agents were well tolerated and reduced blood pressures consistently over the 10-week test period, amlodipine was more effective than diltiazem in reducing systolic and diastolic blood pressures to the target pressures of < 140 mm Hg systolic and < 90 mm Hg diastolic over a range of doses widely used in …
Is amlodipine first line?
Results: Amlodipine has good efficacy and safety, in addition to strong evidence from large randomised controlled trials for cardiovascular event reduction. Conclusions: Amlodipine should be considered a first-line antihypertensive agent.
What is the first choice for high blood pressure?
ACE Inhibitors, or angiotensin receptor blockers (ARBs), are recommended as first line therapy because they lower blood pressure and the risk of stroke and heart disease. ACE inhibitors are cheap, well tolerated medications that end in -il (for example: lisinopril, enalapril, benazepril).