What is the Ocular toxicity?
Ocular toxicity is characterized by one or more adverse changes that affect the structure or function of the eye following application of a substance, drug, or device directly on or in the eye or an alternate site in the body distant to the eye.
What is ocular pesticide exposure?
Ocular exposure to a pesticide means that it gets in the eye. Oral exposure to a pesticide is swallowing or ingesting it. Inhalation exposure is inhaling a pesticide. Using improper personal protective equipment can lead to exposure to the pesticide.
Can cause visual disturbances when toxic?
Ocular adverse effects may be related to the pharmacodynamic or pharmacokinetic action of a drug, possibly even serving as a marker of toxicity. Both temporary visual disturbances and permanent vision loss are possible.
What is Hcq toxicity?
Disease Entity. Hydroxychloroquine (Plaquenil) and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina.
Which class of drug produces Ocular toxicity?
Chlorpromazine is one of the most common psychotropic agents which can potentially induce numerous and diverse unwanted ocular effects. At high dosages, the drug can commonly cause abnormal pigmentation of the eyelids, interpalpebral conjunctiva, lens, and cornea. It can also cause corneal edema [36].
What is corneal exposure?
Exposure keratopathy (also known as exposure keratitis) is damage to the cornea due to dryness caused by incomplete or inadequate eyelid closure, resulting in loss or insufficiency of the tear film. It is usually a mild condition that is simple to treat.
How do you get pesticide poisoning?
Many insecticides can cause poisoning after being swallowed, inhaled, or absorbed through the skin. Symptoms may include eye tearing, coughing, heart problems, and breathing difficulties. The diagnosis is based on symptoms, blood tests, and a description of events surrounding the poisoning.
What happens if you inhale fumigation?
Moderate inhalation exposure can cause weakness, vomiting, chest pain, diarrhea, difficulty breathing and pain just above the stomach. Symptoms of severe inhalation exposure may occur within a few hours to several days after exposure. Severe poisoning may result in fluid in the lungs.
Which drugs produce ocular toxicity?
While this article does not include an exhaustive list, common systemic medications that cause ocular side effects include: bisphosphonates; cyclosporine and tacrolimus; minocycline; hydroxychloroquine; ethambutol; topiramate; tamsulosin; amiodarone; anticholinergics; erectile dysfunction drugs; blood pressure …
What drugs produce ocular toxicity?
What are the reactions to hydroxychloroquine?
Hydroxychloroquine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache.
- dizziness.
- loss of appetite.
- nausea.
- diarrhea.
- stomach pain.
- vomiting.
- rash.