What is intracoronary thrombolysis?
Intracoronary thrombolysis may have a role as an adjunct therapy in highly selected cases in the setting of ST-elevation myocardial infarction, particularly with large thrombus burden, to facilitate revascularization.
What is intracoronary thrombolytic therapy used for?
Intracoronary thrombolysis is used to treat thrombus in coronary aneurysms due to Kawasaki disease [36]. It is effective and safe in STEMI patients with large thrombus burden in ectatic coronary arteries [37].
What is thrombolytic therapy for MI?
Thrombolytic therapy is the use of drugs to break up or dissolve blood clots, which are the main cause of both heart attacks and stroke.
What is pulse infusion?
Definition. Pulse therapy refers to discontinuous intravenous (IV) infusion of high doses of the medication, arbitrarily defined as treatment with more than 250 mg prednisone or its equivalent per day, for one or more days.
What is coronary stent implantation?
Coronary stents are now used in nearly all angioplasty procedures. A stent is a tiny, expandable metal mesh coil. It is put into the newly opened area of the artery to help keep the artery from narrowing or closing again. Once the stent has been placed, tissue will start to coat the stent like a layer of skin.
Do you give tPA for MI?
FDA-approved indications for alteplase include pulmonary embolism, myocardial infarction with ST-segment elevation (STEMI), ischemic stroke when given within 3 hours of the start of symptoms, and re-establishment of patency in occluded intravenous (IV) catheters.
When is thrombolytic therapy used in Michigan?
Thrombolytic therapy is indicated in patients with evidence of ST-segment elevation MI (STEMI) or presumably new left bundle-branch block (LBBB) presenting within 12 hours of the onset of symptoms if there are no contraindications to fibrinolysis.
What is the pulse therapy?
Pulse therapy refers to the administration of a drug intermittently to accelerate the therapeutic efficacy. In other words pulse therapy refers to intravenous infusion of high dose of steroids for one or more days for quicker, better efficacy and to decrease the side effects of long-term steroids.[10,11,12]
What is pulse therapy used for?
Pulse therapy means the administration of large (suprapharmacologic) doses of drugs in an intermittent manner to enhance therapeutic effects and reduce adverse effects. Dexamethasone and cyclophosphamide in bolus doses have been widely used in pulse form to treat various dermatological disorders.
Why is tPA given for MI?
The use of tPA has been associated with improvement in left ventricular function, a lower mortality, and a decrease in congestive heart failure signs and symptoms. A protocol for evaluation of patients with possible myocardial infarction for thrombolytic therapy is presented.