What are the 4 stages of Rett syndrome?
Rett syndrome is commonly divided into four stages:
- Stage I: early onset. Signs and symptoms are subtle and easily overlooked during the first stage, which starts between 6 and 18 months of age and can last for a few months or a year.
- Stage II: rapid deterioration.
- Stage III: plateau.
- Stage IV: late motor deterioration.
Are there different types of Rett syndrome?
There are two main types of Rett syndrome: classic and atypical. The two types may differ by their symptoms or by the specific gene mutation.
What is the life expectancy of Rett?
While it is known that Rett syndrome shortens lifespan, not much is known about specific life expectancy rates for people with Rett syndrome. It generally depends on the age when symptoms first begin and their severity. On average, most individuals with the condition survive into their 40s or 50s.
Is Rett syndrome a form of autism?
Rett syndrome (RTT, MIM#312750) is a neurodevelopmental disorder that is classified as an autism spectrum disorder. Clinically, RTT is characterized by psychomotor regression with loss of volitional hand use and spoken language, the development of repetitive hand stereotypies, and gait impairment.
What do you need to know about Rett syndrome?
Rett syndrome is a neurodevelopmental disorder that affects girls almost exclusively. It is characterized by normal early growth and development followed by a slowing of development, loss of purposeful use of the hands, distinctive hand movements, slowed brain and head growth, problems with walking, seizures,…
What are the mutations that cause Rett syndrome?
Scientists have identified mutations in the CDKL5 and FOXG1 genes in individuals who have atypical or congenital Rett syndrome, but they are still learning how those mutations cause the disorder.
Can a person with Rett syndrome have MECP2?
Not everyone who has an MECP2 mutation has Rett syndrome. Scientists have identified mutations in the CDKL5 andFOXG1 genes in individuals who have atypical or congenital Rett syndrome, but they are still learning how those mutations cause the disorder.
When does scoliosis occur in people with Rett syndrome?
Scoliosis is common with Rett syndrome. It typically begins between 8 and 11 years of age and increases with age. Surgery may be required if the curvature is severe. Irregular heartbeat. This is a life-threatening problem for many children and adults with Rett syndrome and can result in sudden death.
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