Is Pinacolone soluble in water?
Specifications
| Density | 0.803 g/mL |
|---|---|
| Solubility Information | Miscible with water,chloroform,ethanol,ether,acetone and carbon tetrachloride. |
| Formula Weight | 100.16 |
| Percent Purity | 97% |
| Chemical Name or Material | Pinacolone |
What is Pinacolone used for?
Pinacolone is produced in large amounts for use in fungicides, herbicides, and pesticides. retrosynthetic analysis of vibunazole showed that it was derived from pinacolone. It is also used to prepare pinacidil, as well as naminidil. Pivaloylacetonitrile is used in the synthesis of Doramapimod.
What is the formula of Pinacolone?
C6H12O
Pinacolone/Formula
What is the boiling point of Pinacolone?
222.8°F (106°C)
Pinacolone/Boiling point
What is the Iupac name of Pinacolone?
The IUPAC name of Pinacolone is 3,3-dimethyl-2-butanone. Pinacolone is a very important ketone.
How is Pinacol prepared?
Pinacol hydrate can be prepared by the reduction of acetone by means of magnesium amalgam,3 aluminum amalgam,4 sodium,5 sodium amalgam,6 and electrolytically. The catalyzed addition of hydrogen peroxide to tetramethylethylene also furnishes pinacol.
What are the application of pinacol pinacolone rearrangement?
The uses of the pinacolone product produced from the pinacol pinacolone rearrangement include: Pinacolone is used in Pesticides, Fungicides, and Herbicides. Pinacolone is used to prepare the cyanoguanidine drug – pinacidil. Another drug use of Pinacolone is its use in Stiripentol, which is used to treat epilepsy.
What is intermediate in pinacol pinacolone rearrangement?
Pinacol is a 1,2 diol (vicinal diol) whereas Pinacolone is a Ketone. The conversion that gave its name to this reaction is the acid catalyzed elimination of water from Pinacol (2,3-dimethyl-2,3-butanediol) to give Pinacolone (t-butyl methyl ketone). The mechanism involves the formation of a carbocation as intermediate.
What is pinacol Pinacolone rearrangement reaction explain its mechanism?
The pinacol–pinacolone rearrangement is a method for converting a 1,2-diol to a carbonyl compound in organic chemistry. The 1,2-rearrangement takes place under acidic conditions. The name of the rearrangement reaction comes from the rearrangement of pinacol to pinacolone.
What drug does Pinacolone rearrangement synthesize?
Pinacolone is used to prepare the cyanoguanidine drug – pinacidil.
What is pinacol Pinacolone rearrangement explain its mechanism?
Which is Lossen rearrangement reaction?
Typically O-acyl, sulfonyl, or phosphoryl O-derivative are employed. The isocyanate can be used further to generate ureas in the presence of amines or generate amines in the presence of H2O….
| Lossen rearrangement | |
|---|---|
| Reaction type | Rearrangement reaction |
| Identifiers | |
| RSC ontology ID | RXNO:0000156 |