How is succinylcholine packaged?
For immediate injection of single doses for short procedures: ANECTINE (succinylcholine chloride) Injection, 20 mg in each mL. Multiple-dose vials of 10 mL, box of 10 vials (NDC 0781-3009-95). Store in refrigerator at 2° to 8°C (36° to 46°F).
How long is succinylcholine unrefrigerated?
Succinylcholine is available as a 20-mg/mL solution and can be stored for as long as 3 months at room temperature while maintaining 90% of its original activity (slightly more if protected from light).
What type of drug is succinylcholine?
Succinylcholine is a skeletal muscle relaxant for intravenous (IV) administration indicated as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
What company makes succinylcholine?
Drug Label Information
| Establishment | |
| Name | Business Operations |
|---|---|
| Cadila Healthcare Limited | MANUFACTURE(70710-1377) , ANALYSIS(70710-1377) |
How much does succinylcholine cost?
The estimated cost per dose of succinylcholine was $37 (range $9 to $93).
Should succinylcholine be refrigerated?
Succinylcholine Chloride Injection, USP, should be stored in the refrigerator; if unbuffered succinylcholine chloride injection complying with USP pH limits must be stored at room temperature, it should not be kept for longer than four weeks.
Can a nurse give succinylcholine?
The registered nurse (RN) may administer Propofol, Etomidate and neuromuscular blocking agents (only Succinylcholine, Rocuronium and Vecuronium) to the non-intubated patient in a hospital setting for the purpose of rapid sequence intubation when the clinical presentation of impending respiratory failure is imminent.
What kind of injection is succinylcholine chloride injection?
Succinylcholine Chloride Injection – Clinical Pharmacology. Succinylcholine is a depolarizing skeletal muscle relaxant. As does acetylcholine, it combines with the cholinergic receptors of the motor end plate to produce depolarization.
Are there any side effects to taking succinylcholine?
As with other neuromuscular blocking agents, the potential for releasing histamine is present following succinylcholine administration. Signs and symptoms of histamine mediated release such as flushing, hypotension and bronchoconstriction are, however, uncommon in normal clinical usage.
What are the effects of succinylcholine on the myocardium?
Succinylcholine has no direct effect on the myocardium. Succinylcholine stimulates both autonomic ganglia and muscarinic receptors which may cause changes in cardiac rhythm, including cardiac arrest.
When to use succinylcholine for artificial respiration?
Succinylcholine should be used only by those skilled in the management of artificial respiration and only when facilities are instantly available for tracheal intubation and for providing adequate ventilation of the patient, including the administration of oxygen under positive pressure and the elimination of carbon dioxide.