What is Polysorbate 80 used for?
Polysorbate 80 is a synthetic nonionic surfactant used as an excipient in drug formulation. Various products formulated with polysorbate 80 are used in the oncology setting for chemotherapy, supportive care, or prevention, including docetaxel, epoetin/darbepoetin, and fosaprepitant.
What is the density of polysorbate 80?
1.06 g/cm³
Polysorbate 80/Density
Is polysorbate 80 flammable?
Not flammable or combustible. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self contained breathing apparatus for fire fighting if necessary. Hazardous decomposition products formed under fire conditions.
Why is Polysorbate 80 bad for you?
Polysorbate 80 has also been causally linked with an increased risk of blood clots, stroke, heart attack, heart failure, and of tumor growth or recurrence in patients with certain types of cancer .
What is a natural substitute for Polysorbate 80?
Red turkey oil (sulfated castor oil) – this oil is water soluble and helps to emulsify other oils into water. It is one of the most natural emulsifiers. However, it comes in a deep red color, thick texture and a strong smell. Do you know more alternatives to Polysorbate 80?
Is polysorbate 80 and Tween-80 the same?
Tween 80 is also a polyethylene sorbitol ester, otherwise known as Polysorbate 80 or polyoxyethylene sorbitan monooleate. It has a molecular weight of 1.31 kDa and works well as a stabilizer and emulsifier, primarily in cosmetics, pharmaceuticals, and food products.
What is the density of Tween 20?
1.1 g/cm³
Polysorbate 20/Density
Are tweens toxic?
Not a dangerous substance or mixture according to the Globally Harmonised System (GHS). Inhalation May be harmful if inhaled. May cause respiratory tract irritation. May cause skin irritation.
How do I dispose of a Tween 80?
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. For disposal see section 13. Avoid contact with skin and eyes.
Are polysorbates safe?
Health concerns related to the presence of polysorbates and impurities related to this ingredient include cancer (due to ethylene oxide and 1,4 dioxane), skin allergies, developmental toxicity, reproductive toxicity. When polysorbate is “ethoxylated”, it can become contaminated with these dangerous carcinogens.
What foods contain polysorbates?
Polysorbates are sold as a waxy, yellow paste that mixes easily. They are found in shortening, margarine, peanut butter, dry mixes, ice cream, dairy products, and baked goods. Polysorbate 60 can be an effective dough conditioning agent at a level as low as 0.2 percent based on flour weight.