What is Orbitrap mass spectrometer?
In mass spectrometry, Orbitrap is an ion trap mass analyzer consisting of an outer barrel-like electrode and a coaxial inner spindle-like electrode that traps ions in an orbital motion around the spindle.
What does an Orbitrap measure?
Unparalleled sensitivity, resolution, and accuracy Orbitrap technology drives high-resolution, accurate-mass (HRAM) data, generating incredibly high resolution measurements of up to 500,000 FWHM (with the option of achieving up to 1,000,000 FWHM) at m/z 200.
What is LTQ Orbitrap?
LTQ Orbitrap Velos is a hybrid mass spectrometer incorporating the LTQ Velos™ dual cell linear trap and the Orbitrap™ analyzer. The LTQ Orbitrap is a high performance LC-MS and MSn system, combining rapid LTQ ion trap data acquisition with high mass accuracy Orbitrap mass analysis.
What is the difference between ion trap and Orbitrap?
The Orbitrap is a modified Kingdon ion trap that consists of two endcap electrodes and a central “spindle” electrode. Ions entering the Orbitrap are trapped by their attraction to the spindle electrode, which is contrasted by their inertia, and begin to orbit around the spindle electrode.
Who invented Orbitrap?
Alexander Makarov
Alexander Makarov, inventor of the Orbitrap mass analyzer, discuss 20 years of Orbitrap innovations.
How much does AQ exactive cost?
The Average Price for THERMO FISHER SCIENTIFIC Q Exactive – $43,026 Based on 6 Listings of This Product.
When was the Orbitrap invented?
Although the first Orbitrap-based mass spectrometer didn’t enter the market until 2005, the technological principles that underlay its conception date back to 1923, when Kingdon first described orbital trapping using an enclosed metal can and charged wire.
How does a Penning trap work?
Penning traps use a strong homogeneous axial magnetic field to confine particles radially and a quadrupole electric field to confine the particles axially. The magnetic field in combination with the electric field causes charged particles to move in the radial plane with a motion which traces out an epitrochoid.
How does an Orbitrap work?
The Orbitrap is an ion trap mass analyzer that consists of two outer electrodes and a central electrode, which enable it to act as both an analyzer and detector. By measuring the oscillation frequencies induced by ions on the outer electrodes, the mass spectra of the ions are acquired using image current detection.
What property of the ions does an Orbitrap used for detection?
In such instruments, ions are trapped in a strong magnetic field combined with a weak electric field. Image current from coherently excited trapped ions is detected, digitized, and converted using Fourier transform into the frequency domain and then mass spectra.
How Antimatter is stored?
Antimatter in the form of charged particles can be contained by a combination of electric and magnetic fields, in a device called a Penning trap. The record for storing antiparticles is currently held by the TRAP experiment at CERN: antiprotons were kept in a Penning trap for 405 days.
What is cyclotron motion?
A cyclotron is a type of particle accelerator in which charged particles accelerate outwards from the center along a spiral path. The particles are held to a spiral trajectory by a static magnetic field and accelerated by a rapidly varying electric field.
How is an Orbitrap used in mass spectrometry?
In mass spectrometry, Orbitrap is an ion trap mass analyzer consisting of an outer barrel-like electrode and a coaxial inner spindle-like electrode that traps ions in an orbital motion around the spindle.
How does the Orbitrap ion trap mass analyzer work?
The Orbitrap is an ion trap mass analyzer that consists of two outer electrodes and a central electrode, which enable it to act as both an analyzer and detector. Ions entering the Orbitrap are captured through “electrodynamic squeezing,” after which they oscillate around the central electrode and in between the two outer electrodes.
How does Orbitrap work in liquid chromatography?
Orbitrap systems connect to liquid chromatography equipment to enhance separation of unknown and known compounds and enable high-throughput workflows. Thermo Fisher Scientific offers a wide portfolio of Orbitrap-based MS systems, including systems combined with ion traps and quadrupole mass filters, to address all your analysis needs.
How does Thermo Fisher Scientific Orbitrap system work?
Orbitrap systems connect to liquid chromatography equipment to enhance separation of unknown compounds and enable high-throughput workflows. Thermo Scientific offers a wide portfolio of Orbitrap-based MS systems, including systems combined with ion traps and quadrupole mass filters, to address all your analysis needs.